Results 121 to 130 of about 2,555,341 (310)

Pulmonary Function and Influencing Factor Investigation for Rural Homemakers in the Fenwei Plain, China

open access: yesToxics
To understand the pulmonary function and main influencing factors of homemakers in rural Xi’an, a representative city in Northwest China, 72 housewives (61 ± 9 years old) were randomly selected from the rural area of Lantian, Xi’an.
Rong Feng   +6 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Logistic discrimination using robust estimators: an influence function approach

open access: yes, 2008
peer reviewedLogistic regression is frequently used for classifying observations into two groups. Unfortunately there are often outlying observations in a data set and these might affect the estimated model and the associated classification error rate ...
Croux, Christophe   +3 more
core   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Semiparametric Estimators for the Regression Coefficients in the Linear Transformation Competing Risks Models with Missing Cause of Failure

open access: yes, 2006
In many clinical studies, researchers are mainly interested in studying the effects of some prognostic factors on the hazard of failure from a specific cause while individuals may failure from multiple causes.
Gao, Guozhi
core  

The plant microbiota: From theoretical advances to applications

open access: yesFundamental Research
In nature, healthy plants harbor abundant and diverse microbes known as the plant microbiota. These taxonomically structured microbial assemblies contribute to plant growth and health, and extend the capacity of plants to adapt to their environment ...
Weidong Liu   +6 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

An alternative definition of the influence function

open access: yes
We define an asymptotic mean version of Tukey's sensitivity curve. For this we show that some of the more important features of Hampel's influence function hold for L- and M-estimators also.
Schwabe, Rainer, Schlittgen, Rainer
core  

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