Results 151 to 160 of about 13,563,242 (300)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Decomposing low birth weight inequality in Lesotho: A distributional analysis using hybrid Fairlie and recentred influence function methods on multiple indicator cluster survey 2018. [PDF]

J Public Health Afr
Motlamelle TE, Machema RP.
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Influence of Bioimplant Surface Electrical Potential on Osteoblast Behavior and Bone Tissue Formation

Following the general adhesion theory the bone cells attachment to the bioimplant could be controlled by its surface electrical potential. The latter was adjusted both by deposition of the electrical charge and the surface microgeometry.
Khlusov, I., Sammons, R., Dehtjars, Jurijs, Poļaka, Nataļja, Tjuļkins, Fjodors   +4 more
core  

Influence of soft diet feeding on development of masticatory function

, 2006
Stomatognathic function is developed in steps from the latter half of infancy up to childhood. This period is thought to be critical for stomatognathic function acquisition.
Yoshida, Noriaki, Yamada, Yoshiaki, Sanefuji, Kyoko, Yamada, Masahiko, Okayasu, Ichiro, Oi, Kumiko, Koga, Yoshiyuki   +6 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Constructing a quasilinear moving average using the scaling function [PDF]

The scaling function from multiresolution analysis can be used to constuct a smoothing tool in the context of time series analysis. We give a time series smoothing function for which we show the properties of a quasilinear moving average. Furthermore; we
Schlüter, Stephan
core  

Explainable AI (XAI) for Neonatal Pain Assessment via Influence Function Modification. [PDF]

Annu Int Conf IEEE Eng Med Biol Soc
Hossain MI, Zamzmi G, Mouton P, Sun Y, Goldgof D.   +4 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source