Results 91 to 100 of about 3,083,563 (312)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The status and influencing factors of xerostomia in maintenance hemodialysis patients
Linchuang shenzangbing zazhi, 2019 Objective To investigate the status and influencing factors of xerostomia in maintenance hemodialysis( MHD) patients. Methods A random sampling method was used to select 114 patients with MHD from September to October of 2017 in Grade 3 A Hospital of ...
LI A-min +4 more
doaj
BMC Oral HealthObjective To explore the main factors affecting early dental caries among preschool children aged 3–6 years in Xingtai City to formulate effective preventive measures. Methods A cross-sectional study was conducted on 570 preschool children aged 3–6 years
Hua Xu +5 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
PROFESIONALISME GURU DAN FAKTOR-FAKTOR YANG MEMPENGARUHINNYA
GurukuThis research is a qualitative study that uses a literature review with the aim of investigating various references related to factors that influence teachers' professional competence.
Jabar Yasir +3 more
doaj +1 more source
Factors Influencing Economic Growth in Indonesia: Error Correction Model (ECM) [PDF]
, 2015 :The main objective of this study is to identify and analyze the effect of foreign direct investments (FDI), foreign debts, bank credit and labor force on the economic growth in Indonesia. Annual data during the period of 1985-2013 are used in this study
Muqorrobin, Y. (Yahya)
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source