Results 81 to 90 of about 3,083,563 (312)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

FACTORS AFFECTING THE REJECTION OF EVALUATION RADIOGRAPH BLASS NIER OVERZICHT-INTRAVENOUS PYELOGRAFI

open access: yesLINK, 2017
This research due to know the influencing factors of BNO-IVP radiograph rejection and to know the solution of rejection. The researcher using 3 method of data collecting, i.e.
Agi Febrian Trihadijaya   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Factors Influencing the Surprising Instability of Word Embeddings

open access: yes, 2018
Despite the recent popularity of word embedding methods, there is only a small body of work exploring the limitations of these representations. In this paper, we consider one aspect of embedding spaces, namely their stability.
Kummerfeld, Jonathan K.   +2 more
core   +1 more source

New Zealand Building Project Cost and Its Influential Factors: A Structural Equation Modelling Approach [PDF]

open access: yes, 2019
Construction industry significantly contributes to New Zealand's economic development. However, the delivery of construction projects is usually plagued by cost overruns, which turn potentially successful projects into money-losing ventures, resulting in
Liu, Zhansheng   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Urinary antibiotic level and influencing factors in children residing in Jiangsu Province

open access: yesZhongguo shipin weisheng zazhi
ObjectiveTo evaluate the internal exposure level of antibiotics in children and analyze its influencing factors.MethodsQuestionnaires were disseminated and urine samples were collected in June 2022 from kindergarteners and children enrolled in primary ...
WANG Xingchen   +8 more
doaj   +1 more source

Factors Influencing Internal Efficiency of Public Secondary Schools in Bungoma County [PDF]

open access: yes, 2017
Education plays a critical role in promoting economic, social, cultural and political development of individuals, communities, nations and humanities. The Government of Kenya has consequently been allocating substantial resources to the education sector.
Murumbakiveu, N. (Noah)   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Factors Influencing Individual Performance in an Indonesian Government Office [PDF]

open access: yes, 2013
Reformation in Indonesian government offices leads to many substantial changes, and demands improved job performances while arguably loading employees with more work.
Marpaung, S. B. (Sally)   +2 more
core   +3 more sources

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