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Influenza is an infectious respiratory disease that, in humans, is caused by influenza A and influenza B viruses. Typically characterized by annual seasonal epidemics, sporadic pandemic outbreaks involve influenza A virus strains of zoonotic origin. The WHO estimates that annual epidemics of influenza result in ~1 billion infections, 3–5 million cases ...
Florian H Krammer+2 more
exaly +5 more sources
Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Barclay, Wendy S.+17 more
core +14 more sources
A influenza (gripe) é doença infecciosa aguda de origem viral que acomete o trato respiratório e a cada inverno atinge mais de 100 milhões de pessoas na Europa, Japão e Estados Unidos, causando anualmente a morte de cerca de 20 a 40 mil pessoas somente neste último país. O agente etiológico é o Myxovirus influenzae, ou vírus da gripe. Este subdivide-se
Forleo-Neto Eduardo+4 more
openaire +7 more sources
Influenza is the most frequent cause of acute respiratory illness requiring medical intervention because it affects all age groups and because it can recur in any individual. During the past three decades, efforts to prevent and control influenza have focused primarily on the use of inactivated influenza vaccines in elderly people and in individuals ...
Cox, Nancy J., Subbarao, Kanta
openaire +3 more sources
Influenza and the influenza vaccine [PDF]
Influenza, or the “flu,” is an infection caused by the influenza virus. The virus infects the nose and throat, and it can sometimes spread to the lungs. Influenza commonly causes acute fever, cough, chills, tiredness, body aches and, in young children, ear aches.
Joanne M. Langley+2 more
openaire +3 more sources
TIV vaccination modulates host responses to influenza virus infection that correlate with protection against bacterial superinfection [PDF]
Background: Influenza virus infection predisposes to secondary bacterial pneumonia. Currently licensed influenza vaccines aim at the induction of neutralizing antibodies and are less effective if the induction of neutralizing antibodies is low and/or the
Choi, Angela+4 more
core +2 more sources
Increasing uptake of influenza vaccine by pregnant women post H1N1 pandemic: a longitudinal study in Melbourne, Australia, 2010 to 2014 [PDF]
Background: A Melbourne (Australia) university affiliated, tertiary obstetric hospital provides lay and professional education about influenza vaccine in pregnancy annually each March, early in the local influenza season.
McCarthy, Elizabeth Anne+4 more
core +3 more sources