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Memory B cells and CD8⁺ lymphocytes do not control seasonal influenza A virus replication after homologous re-challenge of rhesus macaques. [PDF]
This study sought to define the role of memory lymphocytes in the protection from homologous influenza A virus re-challenge in rhesus macaques. Depleting monoclonal antibodies (mAb) were administered to the animals prior to their second experimental ...
Carroll, Timothy D+4 more
core +17 more sources
2020–2021 rhinovirus genetic diversity in Saint Petersburg
Introduction. Rhinoviruses represent one of the most common respiratory viruses and belong to the Picornoviridae family, genus Enterovirus, being divided into three types: A, B, C, which account for 169 types.
Andrey D. Ksenafontov+7 more
doaj +1 more source
Currently, the assessment of the immunogenic properties of influenza viruses as a part of influenza vaccines is carried out by using seroprotection, seroconversion as well as the rate of increases in post-vaccination antibodies.
V. S. Vakin+9 more
doaj +1 more source
Background. The vaccine is the best available instrument to prevent influenza and reduce the risks of major disease complications and mortality. The vaccine effectiveness during the influenza season depends on a number of factors: (1) a person vaccinated
M. K. Erofeeva+9 more
doaj +1 more source
Antigenic and genetic characteristics of Russian RSV isolates are presented for the first time. Of the 69 strains isolated in St. Petersburg, 93% belonged to the RSV-A antigenic group.
V. Z. Krivitskaya+12 more
doaj +1 more source
TIV vaccination modulates host responses to influenza virus infection that correlate with protection against bacterial superinfection [PDF]
Background: Influenza virus infection predisposes to secondary bacterial pneumonia. Currently licensed influenza vaccines aim at the induction of neutralizing antibodies and are less effective if the induction of neutralizing antibodies is low and/or the
Choi, Angela+4 more
core +2 more sources
Evaluation of the preventive effectiveness of influenza vaccines in St. Petersburg
Background. The influenza vaccination coverage has steadily increased in the Russian Federation. The introduction of new domestic influenza vaccines into practice and the study of their effectiveness are of great importance for public health.
M. K. Erofeeva+8 more
doaj +1 more source
Recombinant viral vectors represent one of the most promising platforms for creating a new generation of vaccines against tuberculosis. We constructed a vaccine candidate based on a cold-adapted influenza vector with a truncated NS1 protein containing an
M. V. Sergeeva+8 more
doaj +1 more source
Causing millions of cases worldwide every year, influenza is one of the most common respiratory infections. The effectiveness of influenza vaccination and the nature of the resulting immune response may vary depending on the vaccine composition and age ...
Zh. V. Buzitskaya+7 more
doaj +1 more source
Relevance. Influenza is characterized by global distribution and the difference in its seasonality in countries with temperate and tropical climates. The importance of studying antigenic variation of influenza viruses due to the fact that changes in the ...
L. S. Karpova+4 more
doaj +1 more source