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Influenza is a major concern for intensivists in all communities in the U.S. While there is considerable concern whether or not the country will be ready for a pandemic influenza, even seasonal influenza poses a major challenge to hospitals. The objective of this review is to summarize current knowledge of influenza with emphasis on the issues that ...
openaire +4 more sources
Role of biobanks in the study of population immunity
Review focuses on estimation of population immunity and effectiveness of vaccination against socially significant influenza infection. Long-term observations of the population immunity, including post-vaccine seroprevalence to influenza are an ...
O. S. Konshina +3 more
doaj +1 more source
Anti-influenza drugs and vaccines have a limited effect due to the high mutation rate of virus genome. The direct impact on the conservative virus genome regions should significantly improve therapeutic effectiveness. The RNA interference mechanism (RNAi)
A. V. Petrova-Brodskaya +11 more
doaj +1 more source
A series of commercial inactivated influenza vaccines (IIVs) used in the Russian National Immunization Program were characterized to evaluate their protective properties on an animal model.
Andrei Shanko +12 more
doaj +1 more source
Risk of Guillain-Barré syndrome after 2010–2011 influenza vaccination [PDF]
Influenza vaccination has been implicated in Guillain Barré Syndrome (GBS) although the evidence for this link is controversial. A case–control study was conducted between October 2010 and May 2011 in seven Italian Regions to explore the relation between
Beghi, E +12 more
core +1 more source
Viral factors in influenza pandemic risk assessment [PDF]
The threat of an influenza A virus pandemic stems from continual virus spillovers from reservoir species, a tiny fraction of which spark sustained transmission in humans.
Barclay, Wendy +18 more
core +4 more sources
Diagnostic markers of hepatic steatosis in patients with chronic viral hepatitis C
Objective was to conduct a comparative analysis of routine clinical and laboratory parameters in two groups of patients with chronic viral hepatitis C (CHC) depending on the presence or absence of hepatic steatosis.Methods and materials.
V. V. Tsvetkov +3 more
doaj +1 more source
Influenza vaccination uptake among people aged over 85 years: an audit of primary care practice in the UK [PDF]
Public health research and national guidelines have advocated for seasonal influenza vaccination in the elderly. General practice has established itself as an ideal setting for the safe administration and monitoring of vaccines.1 Due to waning immune
Arnott, ND, Fitchett, JR
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
EVOLUTIONARY DYNAMICS OF STRUCTURAL AND FUNCTIONAL DOMAINS OF INFLUENZA A VIRUS NS1 PROTEIN
Influenza A virus (IAV) NS1 protein is one of the key viral factors responsible for virus-host interactions. NS1 counteracts host antiviral defense, participates in the processing and export of cellular mRNAs, regulates the activity of viral RNA ...
A. V. Vasin +4 more
doaj +1 more source

