Lung Transplantation in Acute Respiratory Distress Syndrome Caused by Influenza Pneumonia [PDF]
Severe acute respiratory distress syndrome (ARDS) is a life-threatening disease with a high mortality rate. Although many therapeutic trials have been performed for improving the mortality of severe ARDS, limited strategies have demonstrated better ...
Youjin Chang+8 more
doaj +1 more source
Human germinal centres engage memory and naïve B cells after influenza vaccination
Influenza viruses remain a major public health threat. Seasonal influenza vaccination in humans primarily stimulates pre-existing memory B cells, which differentiate into a transient wave of circulating antibody-secreting plasmablasts 1 – 3 . This recall
J. Turner+22 more
semanticscholar +1 more source
Significance Pigs are intermediate hosts for the generation of pandemic influenza virus. Thus, systematic surveillance of influenza viruses in pigs is a key measure for prewarning the emergence of the next pandemic influenza.
Honglei Sun+22 more
semanticscholar +1 more source
Estimation of influenza activity in Vojvodina (Serbia) for five consecutive influenza seasons [PDF]
Background/Aim. After pandemic 2009/10 influenza season, influenza A (H1N1)pdm09, A(H3N2) and B viruses have continued to circulate in the population. The aim of this study was to describe the epidemiological and virological characteristics of influenza ...
Ristić Mioljub+3 more
doaj +1 more source
One-way trip: Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential [PDF]
We hypothesise that some influenza virus adaptations to poultry may explain why the barrier for human-to-human transmission is not easily overcome once the virus has crossed from wild birds to chickens.
Alexander+101 more
core +1 more source
The evolution of human influenza viruses [PDF]
The evolution of influenza viruses results in (i) recurrent annual epidemics of disease that are caused by progressive antigenic drift of influenza A and B viruses due to the mutability of the RNA genome and (ii) infrequent but severe pandemics caused by the emergence of novel influenza A subtypes to which the population has little immunity. The latter
A. R. Douglas+3 more
openaire +3 more sources
Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine [PDF]
Swine influenza A virus is an endemic and economically important pathogen in pigs, with the potential to infect other host species. The hemagglutinin (HA) protein is the primary target of protective immune responses and the major component in swine ...
A. L. Vincent+58 more
core +1 more source
Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species [PDF]
Highly pathogenic avian influenza A viruses (HPAIV) of the H5N1 subtype occasionally transmit from birds to humans and can cause severe systemic infections in both hosts.
García-Sastre, A.+9 more
core +9 more sources
Influenza and memory T cells : how to awake the force [PDF]
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals.
Glezen+12 more
core +3 more sources