Results 21 to 30 of about 7,903,247 (198)
The evolution of human influenza viruses [PDF]
The evolution of influenza viruses results in (i) recurrent annual epidemics of disease that are caused by progressive antigenic drift of influenza A and B viruses due to the mutability of the RNA genome and (ii) infrequent but severe pandemics caused by the emergence of novel influenza A subtypes to which the population has little immunity. The latter
A J, Hay +3 more
openaire +2 more sources
Effectiveness of influenza vaccine in aging and older adults: comprehensive analysis of the evidence [PDF]
Foremost amongst the diseases preventable by vaccination is influenza. Worldwide, influenza virus infection is associated with serious adverse events leading to hospitalization, debilitating complications, and death in elderly individuals ...
Assir N +11 more
core +1 more source
Health care workers (HCWs) may transmit respiratory infection to patients. We assessed evidence for the effectiveness of vaccinating HCWs to provide indirect protection for patients at risk for severe or complicated disease after acute respiratory ...
Gayle P. Dolan +16 more
doaj +1 more source
Pathology of human influenza revisited [PDF]
The pathology of human influenza has been studied most intensively during the three pandemics of the last century, the last of which occurred in 1968. It is important to revisit this subject because of the recent emergence of avian H5N1 influenza in humans as well as the threat of a new pandemic.
Kuiken, Thijs, Taubenberger, JK
openaire +3 more sources
Stalking influenza by vaccination with pre-fusion headless HA mini-stem. [PDF]
Inaccuracies in prediction of circulating viral strain genotypes and the possibility of novel reassortants causing a pandemic outbreak necessitate the development of an anti-influenza vaccine with increased breadth of protection and potential for rapid ...
Carnell, George +24 more
core +1 more source
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells [PDF]
Background: The hemagglutinin (HA) glycoprotein is the principal target of protective humoral immune responses to influenza virus infections but such antibody responses only provide efficient protection against a narrow spectrum of HA antigenic variants ...
Poon Leo L. M. +92 more
core +1 more source
Estimation of influenza activity in Vojvodina (Serbia) for five consecutive influenza seasons [PDF]
Background/Aim. After pandemic 2009/10 influenza season, influenza A (H1N1)pdm09, A(H3N2) and B viruses have continued to circulate in the population. The aim of this study was to describe the epidemiological and virological characteristics of influenza ...
Ristić Mioljub +3 more
doaj +1 more source
Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]
Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Cheung, Linda +39 more
core +2 more sources
This ecological study was developed to evaluate the patterns in hospital morbidity due respiratory diseases among people over 60 years old residing in the State of Paraná, before and after the implementation of vaccination campaigns against influenza ...
Ana Lúcia Mendes Ferrer +2 more
doaj +1 more source

