Results 91 to 100 of about 560,185 (235)

Antigenic variability of influenza viruses A and B isolated from children in Saint-Petersburg in the period 2013–2015

Журнал инфектологии, 2016
Purpose of the study: study of the circulation, isolation and antigenic analysis of influenza viruses A and B in St.-Petersburg in the children aged 0–18 in the seasons 2013–2015.Materials: nasal swabs from children-inpatients from Saint-Petersburg ...
A. P. Petrova, N. A. Konovalova, D. M. Danilenko, T. G. Lobova, M. Yu. Eropkin, A. I. Zheltukhina, A. D. Vasilieva, E. G. Kornilova, V. S. Afanas’eva   +8 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

RESULTS OF MOLECULAR DETECTION AND CHARACTERIZATION OF INFLUENZA AND OTHER RESPIRATORY VIRUSES IN RUSSIA, SEASON 2017–2018

Инфекция и иммунитет, 2018
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A. A. Sominina, D. M. Danilenko, A. B. Komissarov, A. V. Fadeev, M. M. Pisareva, K. A. Stolyarov, L. S. Karpova, E. I. Burtseva, A. V. Vasin   +8 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Incidence of COVID-19 among Vaccinated with Sputnik V and CoviVac Vaccines (Results of the Telephone Survey for the Epidemic Season 2021–2022 in St. Petersburg)

Эпидемиология и вакцинопрофилактика
Relevance. The emergence of a new SARS-COV-2 coronavirus in early 2020 radically changed the seasonal pattern of influenza and other acute respiratory infections worldwide.
M. K. Erofeeva, O. V. Gashinskaya, Zh. V. Buzitskaya, T. G. Zubkova, E. V. Shakhlanskaya, M. A. Stukova, D. A. Lioznov   +6 more
doaj   +1 more source

Promoting Adherence to Influenza Vaccination Recommendations in Pediatric Practice. [PDF]

, 2019
OBJECTIVES: In the United States, nonadherence to seasonal influenza vaccination guidelines for children and adolescents is common and results in unnecessary morbidity and mortality. We conducted a quality improvement project to improve vaccination rates
Cadilla, Adriana, Diaz, Maria Carmen, Franciosi, James P., Hossain, Jobayer, Werk, Lloyd N.   +4 more
core   +1 more source

Influenza A☆

, 2014
The influenza viruses, which contain single-stranded RNA, are classified into three types, A, B, and C and belong to the Orthomyxoviridae family of viruses. Types A and B cause annual epidemics and often pandemics of influenza illness, while type C is a less common disease with fewer symptoms.
Belshan, M.A., Knoop, F.C., Huggett, K.N.   +2 more
openaire   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

PROBLEMS OF ISOLATION, IDENTIFICATION AND ANTIGENIC CHARACTERIZATION OF RECENT HUMAN A(H3N2) INFLUENZA VIRUSES

Вопросы вирусологии, 2018
Human A (H3N2) influenza viruses are distinguished by a high rate of evolution and regularly cause epidemics around the world. Their ability to adapt and to escape from the host's immune response and to change their receptor specificity is very high ...
P. A. Petrova, N. I. Konovalova, D. M. Danilenko, A. D. Vasilieva, M. Yu. Eropkin   +4 more
doaj   +1 more source