Results 131 to 140 of about 587,130 (290)

Understanding spatiotemporal clustering of seasonal influenza in the United States

BMC Infectious Diseases
Background Seasonal influenza exhibits distinct spatiotemporal patterns across the United States, yet the geographic clustering of influenza activity remains incompletely understood.
Louis Yat Hin Chan, Sinead Morris, Norman Hassell, Perrine Marcenac, Alexia Couture, Arielle Colon, Krista Kniss, Alicia Budd, Matthew Biggerstaff, Rebecca Borchering   +9 more
doaj   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

Advanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro, Marco Piazzoni, Ilaria Borghi, Alberto Baeri, Alessandro Fumagalli, Federica Perillo, Hafiz Muhammad Fahad, Martina Ghizzi, Luca Crippa, Gabriella Nicolini, Angela Bentivegna, Daniele Ramazzotti, Valentina Zuliani, Mirko Rivara, Carlo Giorgio Giussani, Andrea Di Cristofori, Guido Cavaletti, Federica Facciotti, Sobhan Sheikhi, Claire Seydoux, Murielle Salome, Peter Cloetens, Alberto Bravin, Paola Coan, Francesco Nicotra, Laura Russo   +25 more
wiley   +1 more source

Initial surveillance of 2009 influenza A(H1N1) pandemic in the European Union and European Economic Area, April-September 2009 [PDF]

, 2010
European Union (EU) and European Economic Area (EEA) countries reported surveillance data on 2009 pandemic influenza A(H1N1) cases to the European Centre for Disease Prevention and Control (ECDC) through the Early Warning and Response System (EWRS ...
Devaux, Isabelle, Gauci, Charmaine, Penttinen, P., ECDC Influenza Surveillance Group, Salminen, Mika, Ammon, A., Kreidl, P., National Coordinators for Influenza Surveillance   +7 more
core  

Protective activity of CR9114 universal antibody isotypes against influenza A virus in vivo

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Influenza can cause diseases of varying severity, sometimes leading to hospitalization or death. One of the most promising strategies aimed at reducing morbidity and preventing the risks of severe consequences of infection is the use of ...
Ekaterina A. Romanovskaya-Romanko, Marina A. Plotnikova, Veronika A. Oleynik, Aram A. Shaldzhyan, Varvara S. Monakhova, Dmitry S. Balabashin, Viktoriya A. Toporova, Teymur K. Aliev, Sergey A. Klotchenko   +8 more
doaj   +1 more source

Influenza [PDF]

Nature, 2011
openaire   +2 more sources

Engineered Nanotopography to Modulate Growth and Signaling of Neuronal Networks

Advanced Functional Materials, EarlyView.
This study examines the interaction between neurons and nanoscale topographies on engineered substrates. Neurons cultured on nanowires, nanopillars and nanoneedles exhibit enhanced neurite outgrowth, form more organized neuronal circuits, and display improved synaptic connectivity, compared to flat substrates.
Hao Nguyen Tran, Kalyan Shobhana, Zlatan Trifunovic, Dan Smith, Michael Stuiber, Chennupati Jagadish, Mirella Dottori, Andrea J. O'Connor, Vini Gautam   +8 more
wiley   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source

Estimating infection attack rates and severity in real-time during an influenza pandemic

, 2011
The 4th ESWI Influenza Conference, Saint-Julian's, Malta, 11-14 September ...
Hung, IFN, Lau, YL, Lin, CK, Wu, JTK, Ho, LM, Ma, E, Ho, ALY, Chu, DKW, Tsang, T, Peiris, JSM, Cowling, BJ, Ho, PL, Leung, GM, Lo, SV, Lee, CK   +14 more
core  

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Influenza and the implications of a pandemic for Malta [PDF]

, 2005
An influenza pandemic is inevitable and recent reports from Southeast Asia on avian influenza viruses infecting humans have served to fuel worries that a new pandemic is near.
Melillo Fenech, Tanya, Farrugia, Ryan, Spiteri, Gianfranco   +2 more
core