BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Applicability of Winthrop Score for the Diagnosis of Influenza A in the Emergency Department of Hospital Pablo Arturo Suárez, January to March of 2018 [PDF]
, 2020 Introduction: In 2010, the Department of Infectious Diseases at Winthrop University Hospital designed a score system for the diagnosis of Legionella pneumonia.
Montesdeoca, Rafael S. +1 more
core
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
MONOCLONAL ANTIBODIES TO HEMAGGLUTININ OF INFLUENZA B VIRUSES VICTORIA EVOLUTIONARY LINEAGE
Вопросы вирусологии, 2018 Co-circulation of two evolutionary distinct lineages of influenza virus in one epidemic season has led to development specific reagents for rapid identification and typing of new isolates.
E. V. Sorokin +2 more
doaj +1 more source
Live‐attenuated influenza vaccine effectiveness against hospitalization in children aged 2–6 years, the first three seasons of the childhood influenza vaccination program in England, 2013/14–2015/16 [PDF]
, 2022 Nicki L. Boddington +6 more
openalex +1 more source
Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen +18 more
wiley +1 more source
Effect of complex therapy with cytokines in flu and respiratory infections for adults
Журнал инфектологии, 2014 The aim of this investigation was to study effect of cytokines in complex therapy of flu and the sharp respiratory diseases complicated and uncomplicated.
L. V. Voloschcuk +5 more
doaj +1 more source
An evaluation of the Zambia influenza sentinel surveillance system, 2011–2017
BMC Health Services Research, 2020 Background Over the past decade, influenza surveillance has been established in several African countries including Zambia. However, information on the on data quality and reliability of established influenza surveillance systems in Africa are limited ...
Paul Simusika +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu +5 more
wiley +1 more source
Preventive vaccination against influenza today
Медицинский совет, 2016 Influenza vaccination is the most strategically justifiable way to protect against influenza which allows toprevent influenza infection and its serious complications, as well as mitigate the impact of influenza epidemics.
O. S. Konshina +3 more
doaj +1 more source