Results 71 to 80 of about 1,276,612 (387)

Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans

Science, 2009
Generation of Swine Flu As the newly emerged influenza virus starts its journey to infect the world's human population, the genetic secrets of the 2009 outbreak of swine influenza A(H1N1) are being revealed.
R. Garten, C. Davis, C. Russell, B. Shu, S. Lindstrom, A. Balish, W. Sessions, Xiyan Xu, E. Skepner, V. Deyde, M. Okomo-Adhiambo, L. Gubareva, J. Barnes, Catherine Bender Smith, S. Emery, M. Hillman, P. Rivailler, James A. Smagala, M. de Graaf, D. Burke, R. Fouchier, C. Pappas, C. Alpuche-Aranda, H. Lopez-Gatell, Hiram Olivera, Irma López, Christopher A. Myers, D. Faix, P. Blair, Cindy Yu, Kimberly M Keene, P. D. Dotson, D. Boxrud, A. Sambol, S. Abid, K. St. George, T. Bannerman, A. Moore, D. J. Stringer, Patricia Blevins, Gail J. Demmler-Harrison, M. Ginsberg, P. Kriner, S. Waterman, S. Smole, H. Guevara, E. Belongia, P. A. Clark, S. Beatrice, R. Donis, J. Katz, L. Finelli, C. Bridges, M. Shaw, D. Jernigan, T. Uyeki, Derek J. Smith, A. Klimov, N. Cox   +58 more
semanticscholar   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Risk of Guillain-Barré syndrome after 2010–2011 influenza vaccination [PDF]

, 2013
Influenza vaccination has been implicated in Guillain Barré Syndrome (GBS) although the evidence for this link is controversial. A case–control study was conducted between October 2010 and May 2011 in seven Italian Regions to explore the relation between
Beghi, E, Benedetti, M D, Chiò, A, D'Alessandro, R, Filippini, G, Galeotti, F, Granieri, E, Itang, study group., Logroscino, G, Massari, M, Pugliatti, M, Raschetti, R, Santuccio, C   +12 more
core   +1 more source

Human seasonal influenza under COVID-19 and the potential consequences of influenza lineage elimination

Nature Communications, 2021
Annual epidemics of seasonal influenza cause hundreds of thousands of deaths, high levels of morbidity, and substantial economic loss. Yet, global influenza circulation has been heavily suppressed by public health measures and travel restrictions since ...
V. Dhanasekaran, S. Sullivan, Kimberly M. Edwards, Ruopeng Xie, A. Khvorov, S. Valkenburg, B. Cowling, I. Barr   +7 more
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

EVOLUTIONARY DYNAMICS OF STRUCTURAL AND FUNCTIONAL DOMAINS OF INFLUENZA A VIRUS NS1 PROTEIN

Вопросы вирусологии, 2017
Influenza A virus (IAV) NS1 protein is one of the key viral factors responsible for virus-host interactions. NS1 counteracts host antiviral defense, participates in the processing and export of cellular mRNAs, regulates the activity of viral RNA ...
A. V. Vasin, A. V. Petrova-Brodskaya, M. A. Plotnikova, V. B. Tsvetkov, S. A. Klotchenko   +4 more
doaj   +1 more source

Prevalence and Genetic Characteristics of Human Bocaviruses Detected in Patients with Acute Respiratory Infections in Bulgaria

International Journal of Microbiology, 2021
Нuman bocaviruses (hBoVs) are often associated with acute respiratory infections (ARIs). Information on the distribution and molecular epidemiology of hBoVs in Bulgaria is currently limited. The objectives of this study were to investigate the prevalence
Neli Korsun, Svetla Angelova, Ivelina Trifonova, Silvia Voleva, Iliana Grigorova, Iren Tzotcheva, Sirma Mileva, Penka Perenovska   +7 more
doaj   +1 more source

Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine [PDF]

, 2014
Swine influenza A virus is an endemic and economically important pathogen in pigs, with the potential to infect other host species. The hemagglutinin (HA) protein is the primary target of protective immune responses and the major component in swine ...
A. L. Vincent, Anderson, Bao, Bowman, Brown, Centers for Disease Control and Prevention, Core Team R, D. F. Burke, Darriba, De Jong, E. Skepner, Edgar, Feng, Fouchier, Garten, Gauger, Harmon, Hinshaw, Houser, Karasin, Kawaoka, Khurana, Kitikoon, Koel, Lewis, Lindstrom, Lorusso, Loving, Maddison, Miller, Montalvao, Myers, N. S. Lewis, Nelson, Nelson, Nfon, Olsen, P. Kitikoon, Paradis, Pena, Polewicz, PyMOL, Röhm, Salmon, Shinde, Skowronski, Smith, Smith, Stamatakis, T. K. Anderson, Tong, Tong, Vincent, Vincent, Vincent, Vincent, Webby, Webby, Ye   +58 more
core   +2 more sources

Barriers of Influenza Vaccination Intention and Behavior – A Systematic Review of Influenza Vaccine Hesitancy, 2005 – 2016

PLoS ONE, 2017
Background Influenza vaccine hesitancy is a significant threat to global efforts to reduce the burden of seasonal and pandemic influenza. Potential barriers of influenza vaccination need to be identified to inform interventions to raise awareness ...
Philipp Schmid, Dorothee Rauber, C. Betsch, Gianni Lidolt, Marie-Luisa Denker   +4 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source