Results 121 to 130 of about 24,579,249 (345)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Bronchiolitis in children ≤ 12 months during the pre-flu season of 2024: A case series

open access: yesSouth African Family Practice
Background: In March 2024, the National Institute for Communicable Diseases (NICD) warned against a respiratory syncytial virus (RSV) outbreak during the pre-flu season, 2024. Globally, RSV is responsible for most respiratory infections in young children.
Marietjie Brits, Hanneke Brits
doaj   +1 more source

The burden of influenza A and B in Mexico from the year 2010 to 2013: An observational, retrospective, database study, on records from the Directorate General of Epidemiology database

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Despite vaccination programs, influenza still represents a significant disease burden in Mexico. We conducted an observational, retrospective analysis to better understand the epidemiological situation of the influenza virus in Mexico.
Ricardo Cortes-Alcala   +9 more
doaj   +1 more source

Influenza and the implications of a pandemic for Malta [PDF]

open access: yes, 2005
An influenza pandemic is inevitable and recent reports from Southeast Asia on avian influenza viruses infecting humans have served to fuel worries that a new pandemic is near.
Farrugia, Ryan   +2 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Burden of Influenza in Patients Visiting Emergency Department for Treatment of Influenza Like Illness at THQ Hospital Shujabad, Pakistan [PDF]

open access: yes, 2020
Background: Viral infection of the respiratory tract is a common illness syndrome in humans. Human respiratory tract is infected by large number of viruses. Self-constraining infections are caused by most of them e.g.
Chaudhry, M. (Mamoona)   +4 more
core  

Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans

open access: yesScience, 2009
Generation of Swine Flu As the newly emerged influenza virus starts its journey to infect the world's human population, the genetic secrets of the 2009 outbreak of swine influenza A(H1N1) are being revealed.
R. Garten   +58 more
semanticscholar   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Etiological structure and clinical manifestations of influenza in Khanty-Mansiysk autonomous District-Ugra

open access: yesЖурнал инфектологии, 2018
The aim of the study was to examine the incidence of influenza in  epidemic seasons from 2000 to 2017 in Khanty-Mansi Autonomous  Okrug — Yugra, analysis of selected pathogens flu, clinical course,  outcomes, risk and contingent.
T. N. Ugleva, V. A. Pahotina
doaj   +1 more source

Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents

open access: yesNew England Journal of Medicine, 2018
BACKGROUND Baloxavir marboxil is a selective inhibitor of influenza cap‐dependent endonuclease. It has shown therapeutic activity in preclinical models of influenza A and B virus infections, including strains resistant to current antiviral agents ...
F. Hayden   +15 more
semanticscholar   +1 more source

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