Results 81 to 90 of about 24,579,249 (345)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Concurrent outbreak of influenza A and dengue infection: a probability analysis for dengue and influenza A coinfection

Egyptian Journal of Chest Disease and Tuberculosis, 2019
The influenza A is an important viral respiratory disease. This infection is seen worldwide and is considered an important global public health problem.
Sora Yasri, Viroj Wiwanitkit
doaj   +1 more source

Five years of monitoring for the emergence of oseltamivir resistance in patients with influenza A infections in the Influenza Resistance Information Study

Influenza and Other Respiratory Viruses, 2018
The Influenza Resistance Information Study (IRIS) was initiated in 2008 to study the emergence of neuraminidase inhibitor (NAI) resistance and the clinical course of influenza in immunocompetent treated and untreated patients.
B. Lina, C. Boucher, A. Osterhaus, A. Monto, M. Schutten, R. Whitley, J. Nguyen-Van-Tam   +6 more
semanticscholar   +1 more source

Decreased influenza activity during the COVID-19 pandemic—United States, Australia, Chile, and South Africa, 2020

MMWR. Morbidity and mortality weekly report, 2020
Transplant recipients are among the groups for whom the updated recommendations for 2020–2021 influenza vaccination should generally be considered essential, notably in the face of the COVID-19 pandemic.
S. Olsen, E. Azziz‐Baumgartner, Alicia P. Budd, L. Brammer, S. Sullivan, R. Pineda, C. Cohen, A. Fry   +7 more
semanticscholar   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Favipiravir, an anti-influenza drug against life-threatening RNA virus infections

Pharmacology and Therapeutics, 2020
Favipiravir has been developed as an anti-influenza drug and licensed as an anti-influenza drug in Japan. Additionally, favipiravir is being stockpiled for 2 million people as a countermeasure for novel influenza strains.
K. Shiraki, T. Daikoku
semanticscholar   +1 more source

[Influenza A pneumonia].

Nederlands tijdschrift voor geneeskunde, 2000
The majority of influenza cases are not associated with complications. Secondary bacterial pneumonia, commonly caused by Streptococcus pneumoniae or Staphylococcus aureus, is well known to most clinicians. Primary influenza viral pneumonia, characterized by rapidly progressive hypoxia and respiratory insufficiency together with non-consolidating ...
Veenstra, R P, Boelen, C C, Zijlstra, J G, Bos, A P, Ligtenberg, J J   +4 more
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Serologic evidence of seasonal influenza A and B in HIV patients on combined antiretroviral therapy in Lagos, Nigeria

African Journal of Laboratory Medicine, 2020
Background: Influenza and HIV are endemic in Nigeria but there is no epidemiological data on the co-infection of influenza A and B among HIV patients. Objective: We investigated seasonal influenza A and B, and co-infection among HIV patients on combined
AbdulAzeez A. Anjorin, Barakat A. Adepoju   +1 more
doaj   +1 more source

Results from the centers for disease control and prevention's predict the 2013-2014 Influenza Season Challenge [PDF]

, 2016
Background: Early insights into the timing of the start, peak, and intensity of the influenza season could be useful in planning influenza prevention and control activities.
Allen, Christopher, Alper, David, Aman, Susan, Anil Kumar, V. S., Aslam, Anoshã, Bakach, Iurii, Barrett, Chris, BASAGNI, Stefano, Biggerstaff, Matthew, Bisset, Keith, Broniatowski, David, Brooks, Logan, Brownstein, John S., Butler, Patrick, Chakraborty, Prithwish, Chandra, Priyadarshini, Chen, Jiangzhuo, Del Valle, Sara Y., Deshpande, Alina, Dredze, Mark, Eggo, Rosalind, Eubank, Stephen, Fairchild, Geoffrey, Farrow, David, Finelli, Lyn, Fox, Spencer, Fung, Isaac Chun Hai, Gambhir, Manoj, Generous, Nicholas, GESUALDO, Francesco, Goldstein, Ed, Hao, Yi, Henderson, Jette, Hickman, Kyle S., Hickmann, Kyle S., Hyman, James M., Hyun, Sangwon, Karspeck, Alicia, Kaup, Hemchandra, Khadivi, Pejman, Krishnan, Ramesh, Laskowski, Kathy, Lewis, Bryan, Lipsitch, Marc, Lum, Kristian, Madhavan, Satish, Marathe, Madhav, Markar, Ashirwad, Mekaru, Sumiko R., Meyers, Lauren Ancel, Nagel, Anna, Nsoesie, Elaine O., Pashley, Bryanne, Paul, Michael, PERRA, NICOLA, Priedhorsky, Reid, Ramakrishnan, Anurekha, Ramakrishnan, Naren, Rosenfeld, Roni, Scarpino, Sam, Schaible, Braydon J., Scott, James, Sexton, Jessica K., Shaman, Jeffrey, Singh, Bismark, Srinivasan, Ravi, STILO, GIOVANNI, Tibshirani, Ryan J., Tozzi, Alberto E., Tse, Zion Tsz Ho, Tsou, Ming Hsiang, VELARDI, Paola, Vespignani, Alessandro, Yang, Wan, Ying, Yuchen, Zhang, Qian   +75 more
core   +1 more source