Results 101 to 110 of about 48,268 (246)

Targeting influenza A virus by splicing inhibitor herboxidiene reveals the importance of subtype-specific signatures around splice sites

open access: yesJournal of Biomedical Science, 2023
Background The association between M segment splicing and pathogenicity remains ambiguous in human influenza A viruses. In this study, we aimed to investigate M splicing in various human influenza A viruses and characterize its physiological roles by ...
Yi-Ju Han   +5 more
doaj   +1 more source

Pandemic (H1N1) 2009 Cluster Analysis: A Preliminary Assessment [PDF]

open access: yes, 2009
Pandemic (H1N1) 2009 virus has been causing major concerns around the world because of its epidemic potential, rapid dissemination, rate of mutations, and the number of fatalities.
Alan Zulich   +6 more
core   +1 more source

From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways

open access: yesAdvanced Sensor Research, Volume 4, Issue 10, October 2025.
Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley   +1 more source

Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign

open access: yesClinics, 2012
lIn 2009, the influenza A (H1N1) virus spread rapidly around the world, causing the first pandemic of the 21st Century. In 2010, there was a vaccination campaign against this new virus subtype to reduce the morbidity and mortality of the disease in some ...
Ana Carolina Cavalcanti Marcos   +6 more
doaj   +1 more source

Orexin Deficiency in Narcolepsy: Molecular Mechanisms, Clinical Phenotypes, and Emerging Therapeutic Frontiers

open access: yesBrain and Behavior, Volume 15, Issue 10, October 2025.
Orexin deficiency drives narcolepsy Type 1, leading to excessive daytime sleepiness, cataplexy, and REM intrusions. This review highlights recent advances (2023–2025) in molecular mechanisms, diagnostics, and emerging orexin‐targeted therapies with the potential for disease modification.
Rameesha Rauf   +9 more
wiley   +1 more source

Influenza A and B viruses in the population of Vojvodina, Serbia [PDF]

open access: yes, 2014
At present, two influenza A viruses, H1N1pdm09 and H3N2, along with influenza B virus co-circulate in the human population, causing endemic and seasonal epidemic acute febrile respiratory infections, sometimes with life-threatening complications.
Elez I.   +10 more
core   +1 more source

Comparison of Molecular Assays for the Rapid Detection and Simultaneous Subtype Differentiation of the Pandemic Influenza A (H1N1) 2009 Virus

open access: yesJournal of Microbiology and Biotechnology, 2012
In April 2009, the H1N1 pandemic influenza virus emerged as a novel influenza virus. The aim of this study was to compare the performances of several molecular assays, including conventional reverse transcription polymerase chain reaction (RT-PCR), two real-time reverse transcription (rRT)-PCRs, and two multiplex RTPCRs.
Mi-Kyung Lee, Hye Ryoun Kim
openaire   +2 more sources

Kinetics of IgA Subtypes and Cytokines in Respiratory Secretions Following Immunization With COVID‐19 Mucosal Vaccine

open access: yesJournal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT The COVID‐19 pandemic highlights the need for mucosal vaccines inducing respiratory secretory IgA (sIgA), as traditional intramuscular vaccines primarily elicit systemic IgG with limited mucosal protection. This study systematically compared mucosal immune responses induced by two authorized COVID‐19 mucosal vaccines: an orally aerosolized ...
Weixin Chen   +10 more
wiley   +1 more source

Household Effects of School Closure during Pandemic (H1N1) 2009, Pennsylvania, USA

open access: yesEmerging Infectious Diseases, 2010
To determine the effects of school closure, we surveyed 214 households after a 1-week elementary school closure because of pandemic (H1N1) 2009. Students spent 77% of the closure days at home, 69% of students visited at least 1 other location, and 79% of
Thomas L. Gift   +11 more
doaj   +1 more source

Assessing Influenza and SARS‐CoV‐2 Coinfection in Brazil: A Comprehensive Study of Patient Outcomes From 2020 to 2023

open access: yesJournal of Medical Virology, Volume 97, Issue 10, October 2025.
ABSTRACT Influenza and SARS‐CoV‐2 are major respiratory pathogens that have impacted global health, sharing similar transmission routes and clinical symptoms. The COVID‐19 pandemic brought attention to coinfection with these viruses, which has been associated with worse clinical outcomes, but the full extent of this impact remains underexplored.
L. T. A. Gaklik, B. M. Carneiro
wiley   +1 more source

Home - About - Disclaimer - Privacy