Results 101 to 110 of about 50,202 (247)
ABSTRACT Background Influenza remains a significant yet under‐prioritized public health challenge in Africa, where unique hurdles such as limited surveillance, variable seasonal patterns, and under‐resourced health systems constrain effective prevention and control. This commentary provides a detailed analysis of the influenza landscape, with a focused
Yula Salifu +2 more
wiley +1 more source
From Heterogeneity to Plasticity: Endothelial Dynamics in Lung Disease
ABSTRACT Endothelial heterogeneity and plasticity play an important role in lung development, homeostasis, and pathology. In recent years, increasing evidence has demonstrated that endothelial dysfunction contributes to the progression of various lung diseases, such as ADRS, PF, PH, and lung developmental disorders.
Van Dung Nguyen, Bisheng Zhou
wiley +1 more source
Respiratory and systematic humoral and cellular immune response of pigs to a heterosubtypic influenza A virus infection [PDF]
The level of heterosubtypic immunity (Het-I) and the immune mechanisms stimulated by a heterosubtypic influenza virus infection were investigated in pigs. Pigs are natural hosts for influenza virus and, like humans, they host both subtypes H1N1 and H3N2.
Bianchi, A.T.J. +2 more
core +1 more source
We report DFSA5Az/DFSA5bio, C5‐azidoacetamide 4‐amino‐2,3‐difluorosialic acid activity‐based probes that trap influenza A viral (IAV) neuraminidases (NA) via a stabilized covalent Tyr‐sialosyl intermediate with hour‐scale reactivation. A bioorthogonal azide enables CuAAC (or one‐step biotin) tagging for activity‐dependent Western‐blot detection at ...
Lemeng Chao +6 more
wiley +1 more source
Background: Influenza A (H1N1) virus is the subtype of influenza A virus that was the most common cause of human influenza (flu) in 2009. Other strains of H1N1 are endemic in pigs (swine influenza) and in birds (avian influenza).
Tareef Fadhil Raham +2 more
doaj +2 more sources
Pandemic (H1N1) 2009 Transmission during Presymptomatic Phase, Japan
During an epidemiologic investigation of pandemic influenza (H1N1) 2009 virus infection in May 2009 in Osaka, Japan, we found 3 clusters in which virus transmission occurred during the presymptomatic phase.
Yoshiaki Gu +5 more
doaj +1 more source
The post-2009 influenza pandemic era : time to revisit antibody immunodominance [PDF]
The current inactivated influenza vaccines rely on the induction of neutralizing antibodies against the head domain of the viral hemagglutinin (HA). The HA head contains five immunodominant antigenic sites, all of which are subject to antigenic drift ...
Caton +6 more
core +1 more source
DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao +8 more
wiley +1 more source
Aloe Polysaccharides Inhibit Influenza A Virus Infection—A Promising Natural Anti-flu Drug
Influenza A virus causes periodic outbreaks and seriously threatens human health. The drug-resistant mutants have shown an epidemic trend because of the abuse of chemical drugs.
Zhenhong Sun +7 more
doaj +1 more source
Influenza A and B viruses in the population of Vojvodina, Serbia [PDF]
At present, two influenza A viruses, H1N1pdm09 and H3N2, along with influenza B virus co-circulate in the human population, causing endemic and seasonal epidemic acute febrile respiratory infections, sometimes with life-threatening complications.
Elez I. +10 more
core +1 more source

