Results 191 to 200 of about 32,598 (225)

Drug design for Influenza A virus subtype H1N1

open access: yesJournal of the Taiwan Institute of Chemical Engineers, 2010
Abstract An outbreak of influenza A virus subtype H1N1, also known as swine flu, in Mexico was occurred in April 2009. To design drugs for treating this epidemic is urgency. In this study, we employed the new sequences (2009) to build the N1 simulation structure by homology modeling, which has been checked for high reliability by Verify Score and ...
Hung-Jin Huang, Calvin Yu-Chian Chen
exaly   +4 more sources

Magnetic Particle Spectroscopy for Detection of Influenza A Virus Subtype H1N1

ACS Applied Materials & Interfaces, 2020
Magnetic nanoparticles (MNPs) with proper surface functionalization have been extensively applied as labels for magnetic immunoassays, carriers for controlled drug/gene delivery, tracers and contrasts for magnetic imaging, etc. Here, we introduce a new biosensing scheme based on magnetic particle spectroscopy (MPS) and the self-assembly of MNPs to ...
Kai Wu   +6 more
openaire   +2 more sources

Identification of an H1N1 subtype of swine influenza virus and serological analysis

open access: yesJournal of Integrative Agriculture, 2019
To investigate the epizootic of swine influenza virus (SIV), 60 nasal swabs were collected from a clinical cases of pig farm in Tai'an City, Shandong Province of China in April 2017. SIV was isolated by inoculating into 10-day-old Special Pathogen Free embryonated eggs and the whole genome was sequenced.
Fa-chao SUN   +9 more
exaly   +3 more sources

Influenza virus A subtype H1N1 is inhibited by methylated β-lactoglobulin

Journal of Dairy Research, 2010
Addition of methylated β-lactoglobulin (Met-BLG) in the medium of MDCK cell lines infected with influenza virus subtype H1N1 reduced hemagglutination activity (HA) in a concentration dependent manner. Antiviral activity of Met-BLG depended on its concentration, viral load, and duration of infection. Using 17 μg/ml of Met-BLG inhibited 50% of HA of H1N1
Sitohy, Mahmoud Zaki   +6 more
openaire   +4 more sources

Efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the classical swine H1N1 subtype influenza virus in mice and pigs

Archives of Virology, 2014
Swine influenza (SI) is an acute, highly contagious respiratory disease caused by swine influenza A viruses (SwIVs), and it poses a potential global threat to human health. Classical H1N1 (cH1N1) SwIVs are still circulating and remain the predominant subtype in the swine population in China.
Feng, Wen   +7 more
openaire   +2 more sources

Age-Associated Cross-reactive Antibody-Dependent Cellular Cytotoxicity Toward 2009 Pandemic Influenza A Virus Subtype H1N1

open access: yesJournal of Infectious Diseases, 2013
Fulltext embargoed for: 12 months post date of publicationBACKGROUND: During the 2009 pandemic of influenza A virus subtype H1N1 (A[H1N1]pdm09) infection, older individuals were partially protected from severe disease. It is not known whether preexisting
Sinthujan Jegaskanda   +2 more
exaly   +2 more sources

Use of health resources due to influenza A virus, H1N1 subtype infection in Brazil

Revista Brasileira de Pesquisa em Saúde/Brazilian Journal of Health Research, 1969
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Ana Paula Accioly   +3 more
openaire   +1 more source

Pandemic 2009 H1N1 Influenza Virus Is Resistant to the Antiviral Activity of Several Interferon Alpha Subtypes

Journal of Interferon & Cytokine Research, 2011
Interferons (IFNs) are critically important in the control of influenza A virus infections. To better understand the pathogenic characteristics of the pandemic 2009 H1N1 influenza virus (pH1N1) from an innate immunity viewpoint, we investigated whether in vitro pH1N1 is sensitive to the antiviral activity of IFN beta, leukocyte IFN alpha, and several ...
SCAGNOLARI, CAROLINA   +9 more
openaire   +3 more sources

[The rescue of H1N1 subtype swine influenza virus].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2009
The swine influenza virus (SIV) strain A/Swine/TianJin/01/2004(H1N1) (A/S/TJ/04) was rescued successfully by an eight-plasmid rescue system. The cDNAs of SIV 8 gene segments were synthesized by RT-PCR and cloned into the RNA polymerase I/II bidirection expression vector PHW2000 independently, resulting in 8 recombinant plasmids.
Yaping, Peng   +3 more
openaire   +1 more source

Epidemiological and virological characterization of influenza A virus subtype H1N1 at tertiary-care hospital, Ahmedabad

International Journal of Medical Science and Public Health, 2016
Background: In April 2009, a new strain of influenza virus, A H1N1, started to spread in various parts of the world, and the first case was reported on May 16, 2009.[1] The associated morbidity and mortality have made it a major health burden. In this study, we have investigated samples of patients with suspected influenza-like illnesses (ILIs ...
Nidhi Barot   +4 more
openaire   +1 more source

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