Results 141 to 150 of about 3,100,016 (354)
Advanced Science, EarlyView.Cardiomyocyte‐enriched USP20 regulates the K63‐linked ubiquitination of STAT3, and the cardiomyocyte‐specific USP20‐STAT3‐CARM1 axis exerts a protective role in cardiac hypertrophy. Targeting USP20 through cardiac‐specific gene therapy presents a promising strategy for the treatment of cardiac hypertrophy.
Lingfeng Zhong +15 more
wiley +1 more source
Acute Encephalopathy Associated with Influenza A Infection in Adults
Emerging Infectious Diseases, 2010 We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence ...
Nelson Lee +10 more
doaj +1 more source
A stochastic model for the evolution of the influenza virus [PDF]
arXiv, 2013 Consider a birth and death chain to model the number of types of a given virus. Each type gives birth to a new type at rate $\lambda$ and dies at rate 1. Each type is also assigned a fitness. When a death occurs either the least fit type dies (with probability $1-r$) or we kill a type at random (with probability $r$).
arxiv
Biomedicine & Pharmacotherapy, 2000 Significant progress has been made in understanding the process of influenza A virus replication in cell culture; however, much less is known about the genetic control of virus-host interactions in disease. This review provides an overview of the genetic analysis of influenza virus biology.
openaire +3 more sources
, 2008 AIM: To determine the effectiveness of serial influenza vaccination. SCOPE: Studied in a Scottish GP population, the overall seroresponse rate increased with annual influenza vaccinations and after 5 years it increased from 45.1% to 93.3% for influenza ...
Carman, WF +4 more
core +1 more source
Advanced Science, EarlyView.In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang +10 more
wiley +1 more source
Advanced Science, EarlyView.Magnetic field‐guided MNP@ATR‐ASO nanocomplexes facilitate the targeted delivery of ASOs to ganglion cells or photoreceptors within retinal explants, thereby enhancing the efficacy of ASOs in correcting pre‐mRNA splicing abnormalities. Furthermore, the nanocomplexes improve ASO penetration and delivery in human retinal and inner ear organoid models ...
Xiuhong Ye +13 more
wiley +1 more source
AI4AI: Quantitative Methods for Classifying Host Species from Avian Influenza DNA Sequence [PDF]
arXiv, 2018 Avian Influenza breakouts cause millions of dollars in damage each year globally, especially in Asian countries such as China and South Korea. The impact magnitude of a breakout directly correlates to time required to fully understand the influenza virus, particularly the interspecies pathogenicity.
arxiv
ANTIGENIC VARIANTS OF INFLUENZA A VIRUS (PR8 STRAIN) [PDF]
, 1956 Paul J. Gerber +2 more
openalex +1 more source
Estimates of the reproduction numbers of Spanish influenza using morbidity data.
, 2007 BACKGROUND: There have been several studies of the transmissibility of the 1918 (Spanish) influenza virus, which has attributed to >20 million deaths.
Mangtani, Punam +2 more
core +1 more source