Results 121 to 130 of about 928,120 (339)

Acute Encephalopathy Associated with Influenza A Infection in Adults

Emerging Infectious Diseases, 2010
We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios >3), and interleukin-6, CXCL10/IP-10, but no evidence ...
Nelson Lee, Chun Kwok Wong, Paul K.S. Chan, Niklas Lindegardh, Nicholas J. White, Frederick G. Hayden, Edward H.C. Wong, Ka Shing Wong, Clive S. Cockram, Joseph J.Y. Sung, David S.C. Hui   +10 more
doaj   +1 more source

One health, multiple challenges: The inter-species transmission of influenza A virus

One Health, 2015
Influenza A viruses are amongst the most challenging viruses that threaten both human and animal health. Influenza A viruses are unique in many ways. Firstly, they are unique in the diversity of host species that they infect. This includes waterfowl (the
K. R. Short, Mathilde Richard, J. Verhagen, D. van Riel, E. Schrauwen, J. V. D. van den Brand, B. Mänz, R. Bodewes, S. Herfst   +8 more
semanticscholar   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Influenza Virus Neuraminidase Structure and Functions

Frontiers in Microbiology, 2019
With the constant threat of emergence of a novel influenza virus pandemic, there must be continued evaluation of the molecular mechanisms that contribute to virulence.
J. McAuley, B. Gilbertson, S. Trifkovic, L. Brown, J. McKimm-Breschkin   +4 more
semanticscholar   +1 more source

Self‐Assembled Inorganic Nanomembrane Tubes: Rolled‐Up Piezoelectrics for Microacoustic Wave‐Based Actuators and Sensors

Advanced Materials, EarlyView.
This study demonstrates a self‐assembly process to generate free‐standing piezoelectric nanomembranes, forming ultracompact microtubular acoustic wave sensors and actuators. The miniaturized 3D piezoelectric platform reported in this work can be applied in telecommunication, energy harvesting, and acoustofluidics. Moreover, the 3D self‐assembly can add
Raphaël C. L‐M. Doineau, Christian N. Saggau, Stefan Baunack, Thomas Gemming, Yara Abdelaal, Robert Weser, Oliver G. Schmidt, Hagen Schmidt, Andreas Winkler, Mariana Medina‐Sánchez   +9 more
wiley   +1 more source

Avian Influenza A(H10N7) Virus–Associated Mass Deaths among Harbor Seals

Emerging Infectious Diseases, 2015
To the Editor: Avian influenza A viruses occasionally cross the species barrier; influenza A(H5N1) virus and the recently emerged influenza A(H7N9) virus are prime examples of bird-to-human transmission (1,2).
R. Bodewes, T. Bestebroer, E. van der Vries, J. Verhagen, S. Herfst, M. Koopmans, R. Fouchier, V. Pfankuche, P. Wohlsein, U. Siebert, W. Baumgärtner, A. Osterhaus   +11 more
semanticscholar   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis.

Lancet Global Health, 2019
BACKGROUND Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (
You Li, R. Reeves, Xin Wang, Q. Bassat, W. A. Brooks, C. Cohen, David P. Moore, M. Nunes, B. Rath, H. Campbell, H. Nair, S. Acácio, W. J. Alonso, Martin Antonio, Guadalupe Ayora Talavera, Darmaa Badarch, V. Baillie, G. Barrera-Badillo, G. Bigogo, S. Broor, D. Bruden, P. Buchy, P. Byass, J. Chipeta, Wilfrido A. Clara, D. Dang, Carla Cecília de Freitas Lázaro Emediato, Menno D. de Jong, J. A. Díaz-Quiñónez, L. A. H. Do, Rodrigo A Fasce, Luzhao Feng, M. Ferson, A. Gentile, B. Gessner, D. Goswami, Sophie Goyet, Carlos G. Grijalva, N. Halasa, Orienka Hellferscee, Danielle Hessong, N. Homaira, Jorge Jara, K. Kahn, N. Khuri-Bulos, K. Kotloff, C. Lanata, Olga López, Maria Renee Lopez Bolaños, Marilla G. Lucero, Florencia Lucion, Socorro Lupisan, S. Madhi, Omphile Mekgoe, Cinta Moraleda, J. Moyes, Kim Mulholland, P. Munywoki, Fathima Naby, T. Nguyen, M. Nicol, D. Nokes, D. Noyola, D. Onozuka, N. Palani, Y. Poovorawan, Mustafizur Rahman, K. Ramaekers, C. Romero, Elizabeth P. Schlaudecker, Brunhilde Schweiger, P. Seidenberg, Eric A F Simoes, R. Singleton, S. Sistla, K. Sturm-Ramirez, N. Suntronwong, A. Sutanto, Milagritos D. Tapia, S. Thamthitiwat, Ilada Thongpan, Gayani Tillekeratne, Y. Tinoco, F. Treurnicht, Claudia Turner, Paul Turner, Rogier H van Doorn, Marc Van Ranst, Benoit Visseaux, Sunthareeya Waicharoen, Jianwei Wang, L. Yoshida, H. Zar   +92 more
semanticscholar   +1 more source