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The Influenza Virus Enigma [PDF]
Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues to kill both people and poultry in Eurasia.
Robert G. Webster, Rachelle Salomon
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Influenza A(H1N1)pdm09 (pH1N1) virus has become established in swine in the United Kingdom and currently co-circulates with previously enzootic swine influenza A virus (IAV) strains, including avian-like H1N1 and human-like H1N2 viruses.
Helen E. Everett+8 more
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Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus
Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with ...
Irene Ramos+7 more
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This infographic briefly summarises the natural history, replication cycle, and pathogenesis of influenza viruses, the cause of seasonal influenza and of influenza pandemics. Influenza viruses infect many vertebrates, with Influenza A, B and C viruses (IAV, IBV, and ICV) infecting humans. High mutation rates allow the evasion of immunity.
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Size and structure of an epistatic space [PDF]
We provide quantitative estimates on the size and the structure of the epistatic space defined in the main article, "Dynamical Correlations in the escape strategy of Influenza A virus", EPL 101 68003.
arxiv +2 more sources
Oseltamivir Prescribing in Pharmacy-Benefits Database, United States, 2004–2005
We reviewed information from a US pharmacy benefits manager database from 2004 through 2005 during periods with little influenza activity. We calculated rates of oseltamivir prescriptions to enrollees. Prescription rates increased significantly from 27.3/
Justin R. Ortiz+6 more
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Influenza Pandemics: Past, Present and Future
Influenza A virus is well known for its capability for genetic changes either through antigen drift or antigen shift. Antigen shift is derived from reassortment of gene segments between viruses, and may result in an antigenically novel virus that is ...
Yu-Chia Hsieh
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Influenza A and B Virus Attachment to Respiratory Tract in Marine Mammals
Patterns of virus attachment to the respiratory tract of 4 marine mammal species were determined for avian and human influenza viruses. Attachment of avian influenza A viruses (H4N5) and (H7N7) and human influenza B viruses to trachea and bronchi of ...
Antonio J. Ramis+4 more
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Prediction of Influenza B Vaccine Effectiveness from Sequence Data [PDF]
Influenza is a contagious respiratory illness that causes significant human morbidity and mortality, affecting 5-15% of the population in a typical epidemic season. Human influenza epidemics are caused by types A and B, with roughly 25% of human cases due to influenza B.
arxiv +1 more source
Prediction of Influenza A virus infections in humans using an Artificial Neural Network learning approach [PDF]
The Influenza type A virus can be considered as one of the most severe viruses that can infect multiple species with often fatal consequences to the hosts. The Haemagglutinin (HA) gene of the virus has the potential to be a target for antiviral drug development realised through accurate identification of its sub-types and possible the targeted hosts ...
arxiv +1 more source