Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses
Nature Communications, 2019 Cytosolic mitochondrial DNA (mtDNA) activates cGAS-mediated antiviral immune responses, but the mechanism by which RNA viruses stimulate mtDNA release remains unknown.
Miyu Moriyama, T. Koshiba, T. Ichinohe
semanticscholar +1 more source
The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses [PDF]
, 2013 In recent years, high pathogenicity avian influenza (HPAI) virus, H5N1, low pathogenicity avian influenza (LPAI) virus, H9N2, and both HPAI and LPAI H7 viruses have proved devastating for the affected economies reliant on poultry industry, and have posed
Böttcher-Frieberthäuser, Eva +5 more
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Influenza pathogenesis: mechanisms of modulation by agent proteins
Журнал инфектологии, 2015 Modern concepts of the influence of the proteins from viruses-etiological agents of flu – Influenzavirus A, B and C (Orthomyxoviridae) – on the development of different elements of the main disease pathogenesis are analyzed in the review.
M. Yu. Shchelkanov +7 more
doaj +1 more source
Obesity Increases the Duration of Influenza A Virus Shedding in Adults
Journal of Infectious Diseases, 2018 Epidemiologic studies indicate that obesity increases the risk of severe complications and death from influenza virus infections, especially in elderly individuals.
H. Maier +10 more
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Development of DNA-Biochip for Identification of Influenza A Virus Subtypes
Проблемы особо опасных инфекций, 2012 Developed was the DNA-biochip to identify subtypes of influenza A virus, pathogenic for humans. Microchip was capable of detecting H1, H3, H5-subtypes of hemagglutinin (including H1-subtype of pandemic A/H1N1(2009) influenza virus ) and neuraminidase ...
A. N. Shikov +8 more
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Инфекция и иммунитет, 2021 Influenza and other acute respiratory viral infections are the most common infectious diseases of our time, causing a significant harm to human health as well as great economic damage.
N. G. Klivleyeva +9 more
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Influenza Vaccination of young children or Antibody Immune Response and Protection after Inactivated Influenza Vaccine in Children – A Literature Review [PDF]
, 2020 Influenza virus infection is a major cause of morbidity and mortality in at risk populations. Children, especially under the age of two, are at an increased risk of complications associated with influenza virus infection.
wall, danielle
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Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites
Nature Communications, 2018 Influenza A virus has an eight-partite RNA genome that during viral assembly forms a complex containing one copy of each RNA. Genome assembly is a selective process driven by RNA-RNA interactions and is hypothesized to lead to discrete punctate ...
Marta Alenquer +5 more
semanticscholar +1 more source
PCR for Detection of Oseltamivir Resistance Mutation in Influenza A(H7N9) Virus
Emerging Infectious Diseases, 2014 Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment.
Wei Wang +8 more
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Direct RNA Sequencing of the Coding Complete Influenza A Virus Genome
Scientific Reports, 2018 For the first time, a coding complete genome of an RNA virus has been sequenced in its original form. Previously, RNA was sequenced by the chemical degradation of radiolabeled RNA, a difficult method that produced only short sequences.
Matthew W. Keller +9 more
semanticscholar +1 more source