Results 51 to 60 of about 928,120 (339)

Canalization of the evolutionary trajectory of the human influenza virus [PDF]

, 2011
Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. Antigenic evolution occurs in the context of a two-dimensional 'antigenic map', while genetic evolution shows a characteristic ladder-like ...
A Kucharski, A Monto, A Park, A Rambaut, Andrew Rambaut, B Adams, B Finkelman, C Viboud, CA Russell, D Weinreich, DJ Smith, E Goldstein, E O'Dea, E Volz, F Carrat, F Tria, G Chowell, G Hirst, IG Barr, J Gog, J Lin, J O'Brien, J Truscott, J Voeten, K Koelle, K Koelle, K Koelle, K Koelle, M Recker, Mercedes Pascual, MI Nelson, NM Ferguson, R Bush, S Bhatt, S Gould, S Kryazhimskiy, S Park, T Bedford, T Bedford, Trevor Bedford, V Gupta, WM Fitch, YI Wolf, Z Yang   +43 more
core   +5 more sources

Influenza and memory T cells : how to awake the force [PDF]

, 2016
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals.
Glezen, Hartshorn, Hufford, Jin, Jordan, Luo, Mosmann, Razvi, Topham, Topham, Topham, Von Andrian, Wijburg   +12 more
core   +3 more sources

Influenza A(H1N1)pdm09 Virus among Healthy Show Pigs, United States

Emerging Infectious Diseases, 2012
Within 5 months after the earliest detection of human influenza A(H1N1)pdm09 virus, we found molecular and culture evidence of the virus in healthy US show pigs. The mixing of humans and pigs at swine shows possibly could further the geographic and cross-
Gregory C. Gray, Jeffrey B. Bender, Carolyn B. Bridges, Russell F. Daly, Whitney S. Krueger, Michael J. Male, Gary L. Heil, John A. Friary, Robin B. Derby, Nancy J. Cox   +9 more
doaj   +1 more source

Novel Reassortant Avian Influenza A(H5N6) Virus, China, 2021

Emerging Infectious Diseases, 2022
Although reports of human infection with influenza A(H5N6) increased in 2021, reports of similar H5N6 virus infection in poultry are few. We detected 10 avian influenza A(H5N6) clade 2.3.4.4b viruses in poultry from 4 provinces in China.
Junhong Chen, Lingyu Xu, Tengfei Liu, Shumin Xie, Ke Li, Xiao Li, Mengmeng Zhang, Yifan Wu, Xinkai Wang, Jinfeng Wang, Keyi Shi, Beibei Niu, Ming Liao, Weixin Jia   +13 more
doaj   +1 more source

Integrating influenza antigenic dynamics with molecular evolution. [PDF]

, 2013
Influenza viruses undergo continual antigenic evolution allowing mutant viruses to evade host immunity acquired to previous virus strains. Antigenic phenotype is often assessed through pairwise measurement of cross-reactivity between influenza strains ...
Abed, Ansaldi, Ansaldi, Barr, Barr, Bedford, Bedford, Bogner, Borodin, Cai, Centers for Disease Control and Prevention, Chakraverty, Chakraverty, Cox, Cox, Daniels, Daum, Daum, Donatelli, Drummond, Edgar, Ferguson, Fitch, Gog, Goldstein, Gust, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hay, Hensley, Hirst, Kanegae, Kendal, Klimov, Koel, Lemey, Li, Lin, Lin, Lin, Lin, Matsuzaki, McCauley, McCauley, McCauley, McCauley, McCauley, McDonald, Muyanga, Nakagawa, Nakajima, Nakajima, Nakajima, Nelson, Nerome, Oh, Osterholm, Pagel, Pereira, Puzelli, Pybus, Raymond, Rota, Russell, Shapiro, Shaw, Smith, Squires, Stevens, Webster, Wiley, World Health Organization, Xu   +83 more
core   +4 more sources

Distribution of influenza virus types by age using case-based global surveillance data from twenty-nine countries, 1999-2014

BMC Infectious Diseases, 2018
Background Influenza disease burden varies by age and this has important public health implications. We compared the proportional distribution of different influenza virus types within age strata using surveillance data from twenty-nine countries during ...
Saverio Caini, Peter Spreeuwenberg, Gabriela F. Kusznierz, Juan Manuel Rudi, Rhonda Owen, Kate Pennington, Sonam Wangchuk, Sonam Gyeltshen, Walquiria Aparecida Ferreira de Almeida, Cláudio Maierovitch Pessanha Henriques, Richard Njouom, Marie-Astrid Vernet, Rodrigo A. Fasce, Winston Andrade, Hongjie Yu, Luzhao Feng, Juan Yang, Zhibin Peng, Jenny Lara, Alfredo Bruno, Doménica de Mora, Celina de Lozano, Maria Zambon, Richard Pebody, Leticia Castillo, Alexey W. Clara, Maria Luisa Matute, Herman Kosasih, Nurhayati, Simona Puzelli, Caterina Rizzo, Herve A. Kadjo, Coulibaly Daouda, Lyazzat Kiyanbekova, Akerke Ospanova, Joshua A. Mott, Gideon O. Emukule, Jean-Michel Heraud, Norosoa Harline Razanajatovo, Amal Barakat, Fatima el Falaki, Sue Q. Huang, Liza Lopez, Angel Balmaseda, Brechla Moreno, Ana Paula Rodrigues, Raquel Guiomar, Li Wei Ang, Vernon Jian Ming Lee, Marietjie Venter, Cheryl Cohen, Selim Badur, Meral A. Ciblak, Alla Mironenko, Olha Holubka, Joseph Bresee, Lynnette Brammer, Phuong Vu Mai Hoang, Mai Thi Quynh Le, Douglas Fleming, Clotilde El-Guerche Séblain, François Schellevis, John Paget, Global Influenza B Study group   +63 more
doaj   +1 more source

Novel Clade 2.3.4.4b Highly Pathogenic Avian Influenza A H5N8 and H5N5 Viruses in Denmark, 2020

Viruses, 2021
Since late 2020, outbreaks of H5 highly pathogenic avian influenza (HPAI) viruses belonging to clade 2.3.4.4b have emerged in Europe. To investigate the evolutionary history of these viruses, we performed genetic characterization on the first HPAI ...
Yuan Liang, Jakob N. Nissen, Jesper S. Krog, Solvej Ø. Breum, Ramona Trebbien, Lars E. Larsen, Charlotte K. Hjulsager   +6 more
doaj   +1 more source

A Seven-Segmented Influenza A Virus Expressing the Influenza C Virus Glycoprotein HEF [PDF]

Journal of Virology, 2008
ABSTRACT Influenza viruses are classified into three types: A, B, and C. The genomes of A- and B-type influenza viruses consist of eight RNA segments, whereas influenza C viruses only have seven RNAs. Both A and B influenza viruses contain two major surface glycoproteins: the hemagglutinin (HA) and the neuraminidase (NA).
Qinshan, Gao, Edward W A, Brydon, Peter, Palese   +2 more
openaire   +2 more sources

Unravelling the Role of O-glycans in Influenza A Virus Infection

Scientific Reports, 2018
The initial stage of host cell infection by influenza A viruses (IAV) is mediated through interaction of the viral haemagglutinin (HA) with cell surface glycans.
Juliane V. Mayr, Kam Y. Lau, J. Lai, I. Gagarinov, Yun Shi, S. McAtamney, R. Chan, J. Nicholls, M. von Itzstein, T. Haselhorst   +9 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source