Results 21 to 30 of about 114,480,210 (307)

Influenza virus activation of the interferon system [PDF]

open access: yes, 2015
This study was supported by the Wellcome Trust (grant number 087751/A/08/Z) and the Medical Research Council (grant number G0700848).The host interferon (IFN) response represents one of the first barriers that influenza viruses must surmount in order to ...
Fodor, Ervin   +8 more
core   +1 more source

Oseltamivir Prescribing in Pharmacy-Benefits Database, United States, 2004–2005

open access: yesEmerging Infectious Diseases, 2008
We reviewed information from a US pharmacy benefits manager database from 2004 through 2005 during periods with little influenza activity. We calculated rates of oseltamivir prescriptions to enrollees. Prescription rates increased significantly from 27.3/
Justin R. Ortiz   +6 more
doaj   +1 more source

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription. [PDF]

open access: yes, 2011
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral genome transcription and replication in the nucleus of infected cells. We recently carried out a proteomic analysis of purified polymerase expressed in human cells and
Juan Ortín   +15 more
core   +2 more sources

Influenza virus A infection of human monocyte and macrophage subpopulations reveals increased susceptibility associated with cell differentiation [PDF]

open access: yes, 2012
Influenza virus infection accounts for significant morbidity and mortality world-wide. Interactions of the virus with host cells, particularly those of the macrophage lineage, are thought to contribute to various pathological changes associated with poor
Jackson David   +27 more
core   +1 more source

Influenza A and D Viruses in Non-Human Mammalian Hosts in Africa: A Systematic Review and Meta-Analysis

open access: yesViruses, 2021
We conducted a systematic review and meta-analysis to investigate the prevalence and current knowledge of influenza A virus (IAV) and influenza D virus (IDV) in non-human mammalian hosts in Africa.
Annie Kalonda   +7 more
doaj   +1 more source

Influenza Pandemics: Past, Present and Future

open access: yesJournal of the Formosan Medical Association, 2006
Influenza A virus is well known for its capability for genetic changes either through antigen drift or antigen shift. Antigen shift is derived from reassortment of gene segments between viruses, and may result in an antigenically novel virus that is ...
Yu-Chia Hsieh
doaj   +1 more source

Influenza A and B Virus Attachment to Respiratory Tract in Marine Mammals

open access: yesEmerging Infectious Diseases, 2012
Patterns of virus attachment to the respiratory tract of 4 marine mammal species were determined for avian and human influenza viruses. Attachment of avian influenza A viruses (H4N5) and (H7N7) and human influenza B viruses to trachea and bronchi of ...
Antonio J. Ramis   +4 more
doaj   +1 more source

INFLUENZA VIRUS TRANSCRIPTION

open access: yesBritish Medical Bulletin, 1978
For some time it has been known that influenza viruses contain a number of distinct single-stranded RNA molecules and in the last few years conclusive evidence has been obtained to indicate that both type A and type B viruses contain eight unique polynucleotide chains.
J J, Skehel, A J, Hay
openaire   +3 more sources

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]

open access: yes, 2014
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K.   +35 more
core   +1 more source

DNA Vaccine Expressing Conserved Influenza Virus Proteins Protective Against H5N1 Challenge Infection in Mice

open access: yesEmerging Infectious Diseases, 2002
Influenza vaccination practice, which is based on neutralizing antibodies, requires being able to predict which viral strains will be circulating. If an unexpected strain, as in the 1997 H5N1 Hong Kong outbreak, or even a pandemic emerges, appropriate ...
Suzanne L. Epstein   +8 more
doaj   +1 more source

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