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Influenza Virus and Vaccination [PDF]

open access: yesPathogens, 2020
Influenza virus infections represent a serious public health problem causing contagious respiratory disease and substantial morbidity and mortality in humans, resulting in a considerable economic burden worldwide. Notably, the number of deaths due to influenza exceeds that of any other known pathogen.
Aitor Nogales, Marta L. DeDiego
openaire   +5 more sources

Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus

open access: yesEmerging Infectious Diseases, 2015
Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with ...
Irene Ramos   +7 more
doaj   +1 more source

Influenza Virus [PDF]

open access: yesTrends in Microbiology, 2018
This infographic briefly summarises the natural history, replication cycle, and pathogenesis of influenza viruses, the cause of seasonal influenza and of influenza pandemics. Influenza viruses infect many vertebrates, with Influenza A, B and C viruses (IAV, IBV, and ICV) infecting humans. High mutation rates allow the evasion of immunity.
openaire   +3 more sources

The Influenza Virus Enigma [PDF]

open access: yesCell, 2009
Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues to kill both people and poultry in Eurasia.
Salomon, Rachelle, Webster, Robert G.
openaire   +2 more sources

The native structure of assembled influenza A virus M1 matrix protein

open access: yesNature, 2020
Influenza A virus causes millions of severe cases of disease during annual epidemics. The most abundant protein in influenza virions is matrix protein 1 (M1), which mediates virus assembly by forming an endoskeleton beneath the virus membrane1.
J. Peukes   +10 more
semanticscholar   +1 more source

Oseltamivir Prescribing in Pharmacy-Benefits Database, United States, 2004–2005

open access: yesEmerging Infectious Diseases, 2008
We reviewed information from a US pharmacy benefits manager database from 2004 through 2005 during periods with little influenza activity. We calculated rates of oseltamivir prescriptions to enrollees. Prescription rates increased significantly from 27.3/
Justin R. Ortiz   +6 more
doaj   +1 more source

Influenza A virus is transmissible via aerosolized fomites

open access: yesNature Communications, 2020
Influenza viruses are presumed, but not conclusively known, to spread among humans by several possible routes. We provide evidence of a mode of transmission seldom considered for influenza: airborne virus transport on microscopic particles called ...
Sima Asadi   +5 more
semanticscholar   +1 more source

Influenza A and D Viruses in Non-Human Mammalian Hosts in Africa: A Systematic Review and Meta-Analysis

open access: yesViruses, 2021
We conducted a systematic review and meta-analysis to investigate the prevalence and current knowledge of influenza A virus (IAV) and influenza D virus (IDV) in non-human mammalian hosts in Africa.
Annie Kalonda   +7 more
doaj   +1 more source

Influenza Pandemics: Past, Present and Future

open access: yesJournal of the Formosan Medical Association, 2006
Influenza A virus is well known for its capability for genetic changes either through antigen drift or antigen shift. Antigen shift is derived from reassortment of gene segments between viruses, and may result in an antigenically novel virus that is ...
Yu-Chia Hsieh
doaj   +1 more source

Influenza A and B Virus Attachment to Respiratory Tract in Marine Mammals

open access: yesEmerging Infectious Diseases, 2012
Patterns of virus attachment to the respiratory tract of 4 marine mammal species were determined for avian and human influenza viruses. Attachment of avian influenza A viruses (H4N5) and (H7N7) and human influenza B viruses to trachea and bronchi of ...
Antonio J. Ramis   +4 more
doaj   +1 more source

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