Improving the identification of antigenic sites in the H1N1 Influenza virus through accounting for the experimental structure in a sparse hierarchical Bayesian model [PDF]
J. R. Stat. Soc. C (2019), 2017 Understanding how genetic changes allow emerging virus strains to escape the protection afforded by vaccination is vital for the maintenance of effective vaccines. In the current work, we use structural and phylogenetic differences between pairs of virus strains to identify important antigenic sites on the surface of the influenza A(H1N1) virus through
arxiv +1 more source
STUDIES ON THE VIRUS OF INFLUENZA [PDF]
Journal of Experimental Medicine, 1936 1. Evidence is presented indicating the presence of a filtrable virus in the nasopharyngeal secretions of individuals suffering from influenza. 2. An attempt to transfer influenza from one human being to another by means of filtered nasopharyngeal washings resulted in the production in the inoculated volunteer of a common cold.
Katherine C. Mills +2 more
openaire +3 more sources
Detection of Evolutionarily Distinct Avian Influenza A Viruses in Antarctica
mBio, 2014 Distinct lineages of avian influenza viruses (AIVs) are harbored by spatially segregated birds, yet significant surveillance gaps exist around the globe. Virtually nothing is known from the Antarctic.
Aeron C. Hurt +10 more
doaj +1 more source
The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses [PDF]
, 2013 In recent years, high pathogenicity avian influenza (HPAI) virus, H5N1, low pathogenicity avian influenza (LPAI) virus, H9N2, and both HPAI and LPAI H7 viruses have proved devastating for the affected economies reliant on poultry industry, and have posed
Böttcher-Frieberthäuser, Eva +5 more
core +3 more sources
Efficient Cavity Searching for Gene Network of Influenza A Virus [PDF]
arXiv, 2022 High order structures (cavities and cliques) of the gene network of influenza A virus reveal tight associations among viruses during evolution and are key signals that indicate viral cross-species infection and cause pandemics. As indicators for sensing the dynamic changes of viral genes, these higher order structures have been the focus of attention ...
arxiv
Current Opinion in Virology, 2020 Influenza D is the only type of influenza virus that mainly affects cattle with frequent spillover to other species. Since the initial description of influenza D virus (IDV) in 2011, the virus has been found to circulate among cattle and swine populations worldwide.
Runxia Liu +4 more
openaire +3 more sources
Influenza Vaccination of young children or Antibody Immune Response and Protection after Inactivated Influenza Vaccine in Children – A Literature Review [PDF]
, 2020 Influenza virus infection is a major cause of morbidity and mortality in at risk populations. Children, especially under the age of two, are at an increased risk of complications associated with influenza virus infection.
wall, danielle
core +1 more source
PCR for Detection of Oseltamivir Resistance Mutation in Influenza A(H7N9) Virus
Emerging Infectious Diseases, 2014 Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment.
Wei Wang +8 more
doaj +1 more source
MC-NN: An End-to-End Multi-Channel Neural Network Approach for Predicting Influenza A Virus Hosts and Antigenic Types [PDF]
, 2023 Influenza poses a significant threat to public health, particularly among the elderly, young children, and people with underlying dis-eases. The manifestation of severe conditions, such as pneumonia, highlights the importance of preventing the spread of influenza.
arxiv +1 more source
Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine [PDF]
, 2014 Swine influenza A virus is an endemic and economically important pathogen in pigs, with the potential to infect other host species. The hemagglutinin (HA) protein is the primary target of protective immune responses and the major component in swine ...
A. L. Vincent +58 more
core +1 more source