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Dynamic Behavior of Avian Influenza A Virus Neuraminidase Subtype H5N1 in Complex with Oseltamivir, Zanamivir, Peramivir, and Their Phosphonate Analogues

Journal of Chemical Information and Modeling, 2009
The outbreak of avian influenza A subtype H5N1 virus has raised a global concern for both animal as well as human health. Recently, drug resistance in H5N1 infections has been widely reported due to neuraminidase mutations. Consequently, the understanding of inhibitor-neuraminidase interactions at the molecular level represents the main goal of our ...
Thanyarat, Udommaneethanakit   +4 more
openaire   +2 more sources

Comparative study of the hemagglutinin and neuraminidase genes of influenza A virus H3N2, H9N2, and H5N1 subtypes using bioinformatics techniques

Canadian Journal of Microbiology, 2007
To investigate the genomic patterns of influenza A virus subtypes, such as H3N2, H9N2, and H5N1, we collected 1842 sequences of the hemagglutinin and neuraminidase genes from the NCBI database and parsed them into 7 categories: accession number, host species, sampling year, country, subtype, gene name, and sequence.
Insung, Ahn, Hyeon S, Son
openaire   +2 more sources

Prokaryotic expression and characterization of avian influenza A virus M2 gene as a candidate for universal recombinant vaccine against influenza A subtypes; specially H5N1 and H9N2

Molecular Biology Reports, 2009
The conserved M2 protein of influenza A virus is considered as a promising candidate target for a broad-spectrum, recombinant influenza A vaccine. In the present study, the open reading frame (ORF) of avian influenza A/chicken/Iran/101/1998 (H9N2) M2 gene was amplified then cloned in pAED4, prokaryotic expression vector. M2 protein was produced through
Seyyed Mahmoud, Ebrahimi   +4 more
openaire   +2 more sources

Comparison of Hemagglutinin and Neruaminidase of Influenza A Virus Subtype H1N1, H5N1, H5N2, and H7N9 Using Apriori Algorithm

2014
The Spanish flu first occurred in 1918 and killed about 50 million people in the world. In 2005, by using gene decoding process, Robert B. Belshe identified that the Spanish flu was occurred by H1N1, which is highly pathogenic influenza A virus. Influenza A virus has been mutated consistently and unexpectedly; H5N1, H5N2, and H7N9 which used to be ...
Dae Young Kim   +3 more
openaire   +1 more source

[Genome sequencing and genetic analysis of a natural reassortant H5N1 subtype avian influenza virus possessing H9N2 internal genes].

Bing du xue bao = Chinese journal of virology, 2010
Abstract:One H5N1 subtype avian influenza virus, A/duck/Shandong/009/2008 (Dk/SD/009/08), was isolated from apparently healthy domestic ducks in some live bird market in East China during our epidemiological surveillance. To investigate the genetic composition, Dk/SD/009/08 was subjected to genome sequencing.
Min, Gu   +6 more
openaire   +1 more source

Re-emergence of fatal human influenza A subtype H5N1 disease

Lancet, The, 2004
Peiris, Jsm, Nicholls, Jm
exaly  

Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus

Lancet, The, 1998
Guus F Rimmelzwaan   +2 more
exaly  

Human infection with highly pathogenic H5N1 influenza virus

Lancet, The, 2008
Andrea Gambotto   +2 more
exaly  

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