Vaccination against human influenza A/H3N2 virus prevents the induction of heterosubtypic immunity against lethal infection with avian influenza A/H5N1 virus. [PDF]
Annual vaccination against seasonal influenza viruses is recommended for certain individuals that have a high risk for complications resulting from infection with these viruses.
Rogier Bodewes +9 more
doaj +1 more source
A Systematic Review and Meta-Analysis of Practices Exposing Humans to Avian Influenza Viruses, Their Prevalence, and Rationale [PDF]
Almost all human infections by avian influenza viruses (AIVs) are transmitted from poultry. A systematic review was conducted to identify practices associated with human infections, their prevalence, and rationale.
Ahad +66 more
core +2 more sources
A Latex Agglutination Test for the Rapid Detection of Avian Influenza Virus Subtype H5N1 and its Clinical Application [PDF]
A rapid and simple latex agglutination test (LAT) for the detection of avian influenza virus (AIV) subtype H5N1 in chicken allantoic fluids, tracheal swabs, and tissues was developed. Monoclonal antibodies against the hemagglutinin glycoprotein of H5N1 were covalently coupled onto the surface of carboxylated latex bead using a water-soluble ...
Jianfeng, Chen +6 more
openaire +2 more sources
Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus [PDF]
The source, timing, and geographical origin of the 1918–1920 pandemic influenza A virus have remained tenaciously obscure for nearly a century, as have the reasons for its unusual severity among young adults.
A. Rambaut +29 more
core +2 more sources
Isolation and Genetic Characterization of Influenza A (Subtype H5N1) Virus from Crows in India [PDF]
We isolated two influenza A (subtype H5N1) viruses from crows in India, in 2011 and 2012. Nucleotide sequence of all eight genome segments of both the viruses (A/crow/India/ 11TI07/2011 and A/crow/India/01TR01/2012) was determined and used for analysis. The two iso - lates shared >99% nucleotide sequence identity in all the eight genes.
openaire +1 more source
Highly Pathogenic Avian Influenza Virus Infection in Feral Raccoons, Japan
Although raccoons (Procyon lotor) are susceptible to influenza viruses, highly pathogenic avian influenza virus (H5N1) infection in these animals has not been reported.
Taisuke Horimoto +9 more
doaj +1 more source
Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary +7 more
wiley +1 more source
Adaptive molecular evolution of virulence genes of avian influenza - A virus subtype H5N1: An analysis of host radiation [PDF]
The phenomenon of host radiation is strongly influenced by the rates of mutation of their virulence genes. We have studied the molecular evolution of virulence genes (HA, NS, PB2) of the Avian Influenza Virus H5N1 from avian to human hosts. We used a site-specific comparison of synonymous (silent) and non-synonymous (amino acid altering) nucleotide ...
Rocky, Kumar +2 more
openaire +2 more sources
Targets of influenza human T-cell response are mostly conserved in H5N1
Frequent recent spillovers of subtype H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI) virus into poultry and mammals, especially dairy cattle, including several human cases, increased concerns over a possible future pandemic.
John Sidney +7 more
doaj +1 more source
Predicting Hotspots for Influenza Virus Reassortment
The 1957 and 1968 influenza pandemics, each of which killed ≈1 million persons, arose through reassortment events. Influenza virus in humans and domestic animals could reassort and cause another pandemic.
Trevon L. Fuller +9 more
doaj +1 more source

