Results 71 to 80 of about 231,038 (305)

Effectiveness of an influenza vaccine programme for care home staff to prevent death, morbidity, and health service use among residents: cluster randomised controlled trial [PDF]

, 2006
Objective To determine whether vaccination of care home staff against influenza indirectly protects residents.Design Pair matched cluster randomised controlled trial.Setting Large private chain of UK care homes during the winters of 2003-4 and 2004-5 ...
Harling, R, Hayward, AC, Johnson, AM, Munro, S, Murad, S, Smedley, J, Watson, JM, Wetten, S   +7 more
core  

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

H5N1 influenza vaccine formulated with AS03A induces strong cross-reactive and polyfunctional CD4 T-cell responses [PDF]

, 2010
Objective Adjuvantation of an H5N1 split-virion influenza vaccine with AS03(A) substantially reduces the antigen dose required to produce a putatively protective humoral response and promotes cross-clade neutralizing responses.
Moris, Philippe, van der Most, Robbert, Leroux-Roels, Isabel, Clement, Frédéric, Dramé, Mamadou, Hanon, Emmanuel, Leroux-Roels, Geert, Van Mechelen, Marcelle   +7 more
core   +2 more sources

Adjuvanted influenza vaccines [PDF]

Human Vaccines & Immunotherapeutics, 2018
In spite of current influenza vaccines being immunogenic, evolution of the influenza virus can reduce efficacy and so influenza remains a major threat to public health. One approach to improve influenza vaccines is to include adjuvants; substances that boost the immune response.
John S. Tregoning, Ryan F. Russell, Ekaterina Kinnear   +2 more
openaire   +5 more sources

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Increasing influenza vaccination rates in solid organ transplant recipients in an outpatient transplant centre

Proceedings of Singapore Healthcare, 2020
Although influenza can lead to significant morbidity and mortality in solid organ transplant recipients, its vaccination rate among solid organ transplant recipients remains low.
Yan Ting Yeo, Jielin Song, Eleanor Gek Theng Ng, Nuraini Lee Binte Ismail Lee, Terence Yi Shern Kee, Chee Kiat Tan, Petrina Yuen Wai Fan, Puay Hoon Lee   +7 more
doaj   +1 more source

The effectiveness of national influenza vaccination policies for at-risk populations over 5 seasons in a Scottish general practice.

, 2008
AIM: To determine the effectiveness of serial influenza vaccination. SCOPE: Studied in a Scottish GP population, the overall seroresponse rate increased with annual influenza vaccinations and after 5 years it increased from 45.1% to 93.3% for influenza ...
Carman, WF, Douglas, J, MacIntyre, S, Selvaraj, S, Sivaprakasam, V   +4 more
core   +1 more source

A prospective cohort study comparing the reactogenicity of trivalent influenza vaccine in pregnant and non-pregnant women [PDF]

, 2015
Background: Influenza vaccination during pregnancy can prevent serious illness in expectant mothers and provide protection to newborns; however, historically uptake has been limited due to a number of factors, including safety concerns.
A Legge, AK Regan, AL Naleway, Annette K Regan, C Yuet Sheung Yuen, CA Peschken, Caroline Talbot, Christopher C Blyth, D Carcione, DB Fell, Donna B Mak, EO Kharbanda, Geoffrey Shellam, IH Russo, JD Nordin, JD Nordin, JR Russo, KE Wiley, Lauren Tracey, M Henninger, MJ Bartlett, P Duclos, Paul V Effler, Peter C Richmond, PL Moro, PV Effler, RA Bednarczyk, SE Haberg, SE Taksdal, World Health Organisation   +29 more
core   +2 more sources

Adjuvanted influenza vaccines

Expert Review of Vaccines, 2013
Influenza is one of the most common causes of human morbidity and mortality that is preventable by vaccination. Immunization with available vaccines provides incomplete protection against illness caused by influenza virus, especially in high-risk groups such as the elderly and young children.
Orli, Even-Or, Sarit, Samira, Ronald, Ellis, Eli, Kedar, Yechezkel, Barenholz   +4 more
openaire   +2 more sources

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source