Results 91 to 100 of about 557,898 (308)

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

Advanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei, Changning Xue, Mengna Li, Jianxia Wei, Lemei Zheng, Shipeng Chen, Yijie Wang, Yumei Duan, Yanwei Luo, Wei Xiong, Ming Zhou   +10 more
wiley   +1 more source

Factors Influencing Childhood Influenza Vaccination: A Systematic Review

Vaccines
Childhood influenza vaccination coverage remains low in lower/middle-income countries. This systematic review aims to identify influencing factors around childhood influenza vaccination. A systematic literature review was conducted and included empirical
Kaiyi Han, Zhiyuan Hou, Shiyi Tu, Mengyun Liu, Tracey Chantler, Heidi Larson   +5 more
doaj   +1 more source

3258 The Relationship Between the Severity of Influenza-Related Illness and Timing of Seasonal Influenza Vaccination in Hospitalized Patients with Influenza

Journal of Clinical and Translational Science, 2019
OBJECTIVES/SPECIFIC AIMS: The overall goal of this project is to determine whether timing of seasonal influenza vaccination affects the severity of illness in vaccinated individuals who are hospitalized with influenza.
Julia Haston, Shikha Garg, Angela Campbell, Jill Ferdinands, Monica Farley, Evan Anderson   +5 more
doaj   +1 more source

ECONOMIC AND BEHAVIORAL FACTORS IN AN INDIVIDUALfS DECISION TO TAKE THE INFLUENZA VACCINATION IN JAPAN [PDF]

In this paper, we investigate what people in Japan consider when deciding to take the influenza vaccination. We develop an economic model to explain the mechanism by which people decide to take the influenza vaccination.
Yoshiro Tsusui, Uri Benzion, Shosh Shahrabani   +2 more
core  

Sonoselective Transfection of Glioma Endothelium

Advanced Science, EarlyView.
Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski, Catherine M. Gorick, Victoria R. Breza, Jackson Tirrell, Krishan Perumal, Katherine M. Nowak, Ji Song, Natasha D. Sheybani, Richard J. Price   +8 more
wiley   +1 more source

Influenza, Campylobacter and Mycoplasma infections, and hospital admissions for Guillain-Barré syndrome, England. [PDF]

, 2006
Guillain-Barré syndrome (GBS) is the most common cause of acute flaccid paralysis in polio-free regions. Considerable evidence links Campylobacter infection with GBS, but evidence that implicates other pathogens as triggers remains scarce. We conducted a
O'Brien, Sarah J, Tam, CC, Sarah J. O’Brien, Laura Rodrigues, Tam, Clarence C, Rodrigues, Laura C, Sarah O'Brien, O'Brien, SJ, Laura C. Rodrigues, Rodrigues, LC., Clarence C. Tam, Clarence Tam   +11 more
core   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Influenza Vaccination Coverage among Registered Nurses in China during 2017–2018: An Internet Panel Survey

Vaccines, 2019
Influenza vaccination is recommended for nurses in China but is not mandatory or offered free of charge. The main objective of this study was to determine influenza vaccination coverage and the principal factors influencing influenza vaccination among ...
Jianxing Yu, Xiang Ren, Chuchu Ye, Keqing Tian, Luzhao Feng, Ying Song, Benjamin J. Cowling, Zhongjie Li   +7 more
doaj   +1 more source

Modelling control of avian influenza in poultry: the link with data [PDF]

, 2009
In this paper the authors discuss the use of modelling in the evaluation of strategies designed to control epidemics of highly pathogenic avian influenza (HPAI) in poultry.
Jong, M.C.M., de, Hagenaars, T.H.J., de Jong, M.C.M.   +2 more
core  

A Single Immunization with Soluble Recombinant Trimeric Hemagglutinin Protects Chickens against Highly Pathogenic Avian Influenza Virus H5N1 [PDF]

, 2010
Background: The highly pathogenic avian influenza (HPAI) virus H5N1 causes multi-organ disease and death in poultry, resulting in significant economic losses in the poultry industry.
Dep Infectieziekten Immunologie, Robert P de Vries, Vries, R.P., de, Rigter, A., Rottier, P.J.M., Cornelissen, A.H.M., de Vries, R.P., Cornelissen, L.A.H.M., Alan Rigter, Cornelis A M de Haan, Strategic Infection Biology, de Haan, C.A.M., Haan, C.A.M., de, de Boer-Luijtze, E.A., Boer-Luijtze, E.A., de, Lisette A H M Cornelissen, Els A de Boer-Luijtze, Peter J M Rottier   +17 more
core   +3 more sources