Results 251 to 260 of about 282,997 (350)

Mass‐Standardised Differential Antibody Binding to a Spectrum of SARS‐CoV‐2 Variant Spike Proteins: Wuhan, Alpha, Beta, Gamma, Delta, Omicron BA.1, BA.4/5, BA.2.75 and BA.2.12.1 Variants—Antibody Immunity Endotypes

open access: yesImmunology, EarlyView.
Fully quantitative, mass‐standardised, antibody responses to ten SARS‐CoV‐2 variants show significant variation in immunity profiles or endotypes. The incidence of the complete response to all variants is significantly improved after three vaccinations.
Philip H. James‐Pemberton   +6 more
wiley   +1 more source

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui   +11 more
wiley   +1 more source

Boosting the influenza vaccine schedule in children with cancer: a prospective open-label study. [PDF]

open access: yesNPJ Vaccines
Chiu SK   +11 more
europepmc   +1 more source

A comparison of super‐resolution microscopy techniques for imaging tightly packed microcolonies of an obligate intracellular bacterium

open access: yesJournal of Microscopy, EarlyView.
Abstract Conventional optical microscopy imaging of obligate intracellular bacteria is hampered by the small size of bacterial cells, tight clustering exhibited by some bacterial species and challenges relating to labelling such as background from host cells, a lack of validated reagents, and a lack of tools for genetic manipulation.
Alison J. North   +7 more
wiley   +1 more source

Immunogenicity of one dose and two doses of adjuvanted influenza vaccine in lung transplant candidates. [PDF]

open access: yesPLoS One
Polishchuk V   +14 more
europepmc   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

open access: yesJournal of Internal Medicine, EarlyView.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron   +3 more
wiley   +1 more source

Influenza vaccine effectiveness and genetic diversity: insights from end-of-season community surveillance, France, 2024-2025. [PDF]

open access: yesEmerg Microbes Infect
Clercq A   +18 more
europepmc   +1 more source

Effectiveness of a pay-it-forward intervention compared with user-paid vaccination to improve influenza vaccine uptake and community engagement among children and older adults in China: a quasi-experimental pragmatic trial

open access: green
Dan Wu   +24 more
openalex   +1 more source

Age at Onset and Delays in Diagnosis of Central Disorders of Hypersomnolence Over the Past 30 Years

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Patients with narcolepsy type 1 (NT1), type 2 (NT2), idiopathic hypersomnia (IH) usually suffer from symptoms for years, even decades, before being diagnosed. We aimed to assess age at onset, age at diagnosis and changes in the diagnostic delays of these patients from 1990 to 2020 in a single centre.
Zhongxing Zhang   +4 more
wiley   +1 more source

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