Results 251 to 260 of about 885,970 (344)

The 15‐Year Survival Advantage: Immune Resilience as a Salutogenic Force in Healthy Aging

open access: yesAging Cell, EarlyView.
Human aging shows puzzling diversity: similar aging rates yet vastly different health outcomes. Our study of ~17,500 people revealed a health‐promoting trait (more common in women) linked to strong immune resilience and high expression of TCF7, a key immune gene. This trait enables individuals to fight infections like COVID‐19 more effectively, respond
Muthu Saravanan Manoharan   +176 more
wiley   +1 more source

Immunosenescence Profile Is Associated With Increased Susceptibility to Severe COVID‐19

open access: yesAging Cell, EarlyView.
(A) A previous immunosenescence profile in individuals infected with SARS‐CoV2 creates a permissive environment for progression to severe COVID‐19: higher inflammaging, accumulation of exhausted/senescent T cells, an oligoclonal B‐cell repertoire, and accelerated epigenetic age.
Lucas Haniel A. Ventura   +40 more
wiley   +1 more source

Use of equine H3N8 hemagglutinin as a broadly protective influenza vaccine immunogen. [PDF]

open access: yesNPJ Vaccines
Verhoeven D   +5 more
europepmc   +1 more source

Aging Compromises Terminal Differentiation Program of Cytotoxic Effector Lineage and Promotes Exhaustion in CD8+ T Cells Responding to Coronavirus Infection

open access: yesAging Cell, EarlyView.
In a MHV infection model with age‐associated increased mortality, we demonstrate that aging impairs, instead of promoting, the terminal differentiation program of virus‐specific CD8+ T cells through downregulating key transcriptional regulators of terminal differentiation.
Ziang Zhu   +8 more
wiley   +1 more source

Immunogenicity and Reactogenicity of High- or Standard-Dose Influenza Vaccine in a Second Consecutive Influenza Season. [PDF]

open access: yesJ Infect Dis
Bahakel H   +31 more
europepmc   +1 more source

Lichen Planus Following COVID‐19 Infection and Vaccination. Matched Case–Control Study

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Background New‐onset lichen planus (LP) development following COVID‐19 infection/vaccination is reported. Since case series cannot be used to study exposure–outcome associations, we designed this matched case–control study to investigate whether COVID‐19‐related events and de novo LP are associated.
Paolo Giacomo Arduino   +4 more
wiley   +1 more source

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