Results 311 to 320 of about 885,970 (344)

A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes

Science, 2022
Seasonal influenza vaccines offer little protection against pandemic influenza virus strains. It is difficult to create effective prepandemic vaccines because it is uncertain which influenza virus subtype will cause the next pandemic.
C. P. Arevalo, M. Bolton, Valerie Le Sage, Naiqing Ye, Colleen Furey, Hiromi Muramatsu, M. Alameh, N. Pardi, E. Drapeau, Kaela Parkhouse, Tyler A. Garretson, J. S. Morris, L. Moncla, Ying K. Tam, Steven H. Y. Fan, S. Lakdawala, D. Weissman, S. Hensley   +17 more
semanticscholar   +1 more source

The Dual Epidemics of COVID-19 and Influenza: Vaccine Acceptance, Coverage, and Mandates.

Journal of the American Medical Association (JAMA), 2020
The confluence of coronavirus disease 2019 (COVID-19) and seasonal influenza this fall and winter will result in considerable morbidity and mortality, stressing the health system.
L. Gostin, D. Salmon
semanticscholar   +1 more source

Influenza vaccines

Frontiers in Bioscience, 2008
Influenza viruses pose a major challenge to those concerned with global public health. Not only do influenza viruses cause yearly epidemics that are associated with slight changes in viral antigenicity, but occasionally new viruses cross from animal reservoirs into humans causing major pandemics.
Richard John, Webby, Matthew Robert, Sandbulte   +1 more
openaire   +2 more sources

Is a Universal Influenza Virus Vaccine Possible?

Annual Review of Medicine, 2020
Influenza viruses remain a severe burden to human health because of their contribution to overall morbidity and mortality. Current seasonal influenza virus vaccines do not provide sufficient protection to alleviate the annual impact of influenza and ...
Raffael Nachbagauer, P. Palese
semanticscholar   +1 more source

Influenza: The Vaccines

Hospital Practice, 1971
The extreme antigenic lability of the influenza A viruses accounts for the less-than-ideal immune responses to them. With a possible swine flu pandemic in the offing, the "vaccine strategy" required is critical, particularly as the medical and public health communities in the United States embark on the first systematic attempt in history to blunt ...
openaire   +3 more sources

Influenza Vaccine Effectiveness: Defining the H3N2 Problem.

Clinical Infectious Diseases, 2019
Observational studies have consistently shown that influenza vaccine effectiveness is lower for H3N2 relative to H1N1pdm09 and type B, and this is not entirely explained by antigenic match.
E. Belongia, H. McLean
semanticscholar   +1 more source