Results 311 to 320 of about 1,044,515 (400)

Evaluating VEGFR2 as a Target for Anti‐Tumour Therapy in Canine Melanoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Vascular endothelial growth factor receptor 2 (VEGFR2) is a key target for anti‐angiogenic oncotherapy, as inhibiting this receptor on tumour vasculature slows tumour development and enhances drug‐ and immune infiltration, improving therapy outcome.
Esther Hindriks, Wilhelmina Bergmann, Aitor Martínez Ruiz, Maurice M. J. M. Zandvliet, Alice J. A. M. Sijts, Femke Broere   +5 more
wiley   +1 more source

Immunogenicity of one dose and two doses of adjuvanted influenza vaccine in lung transplant candidates. [PDF]

PLoS One
Polishchuk V, Kostinov М, Ryzhov А, Dagil Y, Khrapunova I, Zhestkov A, Tarabrin E, Karchevskaya N, Vlasenko A, Kostinova A, Poddubikov A, Solovieva I, Khamidulina A, Prutskova E, Mekhantseva I.   +14 more
europepmc   +1 more source

Management of Haws Syndrome in Cats With Gastrointestinal Diet: A Case Series

Veterinary Ophthalmology, EarlyView.
ABSTRACT Background Haws syndrome (HS) in cats is characterized by bilateral protrusion of the third eyelid and ptosis, often accompanied by gastrointestinal (GI) symptoms such as diarrhea. Emerging evidence suggests disruption of the gut‐brain axis, linked to GI microbiota dysbiosis, may play a role in HS development.
Bar Fruchter, Sharon Kuzi, Yamit Soueid, Oren Pe'er, Ron Ofri, Lionel Sebbag   +5 more
wiley   +1 more source

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

Advanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man, Lin Du, Ying Liu, Zehan Pang, Hongyan Zhu, Bixia Hong, Zhichao Xu, Huahao Fan   +7 more
wiley   +1 more source

Influenza vaccine effectiveness and genetic diversity: insights from end-of-season community surveillance, France, 2024-2025. [PDF]

Emerg Microbes Infect
Clercq A, Blanquart F, Vieillefond V, Visseaux B, Chakra CNA, Nunes MC, Jacques A, Haim-Boukobza S, Wehrle V, Deleglise G, Duret T, Bernard-Stoecklin S, Bercoff DP, Lina B, Rameix-Welti MA, Josset L, Enouf V, Bal A, RELAB study group.   +18 more
europepmc   +1 more source

Large language models for bioinformatics

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract With the rapid advancements in large language model technology and the emergence of bioinformatics‐specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational characteristics, and diverse applications.
Wei Ruan, Yanjun Lyu, Jing Zhang, Jiazhang Cai, Peng Shu, Yang Ge, Yao Lu, Shang Gao, Yue Wang, Peilong Wang, Lin Zhao, Tao Wang, Yufang Liu, Luyang Fang, Ziyu Liu, Zhengliang Liu, Yiwei Li, Zihao Wu, Junhao Chen, Hanqi Jiang, Yi Pan, Zhenyuan Yang, Jingyuan Chen, Shizhe Liang, Wei Zhang, Terry Ma, Yuan Dou, Jianli Zhang, Xinyu Gong, Qi Gan, Yusong Zou, Zebang Chen, Yuanxin Qian, Shuo Yu, Jin Lu, Kenan Song, Xianqiao Wang, Andrea Sikora, Gang Li, Xiang Li, Quanzheng Li, Yingfeng Wang, Lu Zhang, Yohannes Abate, Lifang He, Wenxuan Zhong, Rongjie Liu, Chao Huang, Wei Liu, Ye Shen, Ping Ma, Hongtu Zhu, Yajun Yan, Dajiang Zhu, Tianming Liu   +54 more
wiley   +1 more source

High-Dose vs. Standard-Dose Influenza Vaccine in Older Patients With Hypertension: A Post Hoc Analysis of DANFLU-1. [PDF]

J Clin Hypertens (Greenwich)
Langhoff AF, Johansen ND, Modin D, Janstrup KH, Bartholdy KV, Espersen C, Nealon J, Samson S, Loiacono MM, Harris R, Larsen CS, Jensen AMR, Landler NE, Claggett BL, Solomon SD, Landray MJ, Gislason GH, Køber L, Sivapalan P, Jensen JUS, Biering-Sørensen T.   +20 more
europepmc   +1 more source

Vaccine Name Framing, Relationship Status, and Fear: Examining Heterosexual Men's Intention to Vaccinate Against Human Papillomavirus Infection

World Medical &Health Policy, Volume 18, Issue 1, March 2026.
ABSTRACT Against the backdrop of calling for nonfemale‐oriented promotion of vaccination against human papillomavirus (HPV), this study explored three potential names—“HPV Vaccine,” “Cervical Cancer Vaccine,” and “Genital Warts Vaccine”—to promote vaccination against HPV infection among heterosexual men.
Timothy K. F. Fung, Judy Yuen‐man Siu, Ho Man Leung   +2 more
wiley   +1 more source

Different antigenic distance metrics generate similar predictions of influenza vaccine response breadth despite moderate correlation. [PDF]

PLoS Comput Biol
Billings WZ, Ge Y, Skarlupka AL, Miller SL, Hemme H, John M, Dean NE, Cobey S, Cowling BJ, Shen Y, Ross TM, Handel A.   +11 more
europepmc   +1 more source