Results 161 to 170 of about 207,197 (306)

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Nudges to Clinicians and Patients for Influenza Vaccines During Visits: The BE IMMUNE Randomized Clinical Trial. [PDF]

JAMA Intern Med
Mehta SJ, Waddell KJ, Linn KA, Brophy C, Liang J, Park SH, Reitz C, Williams K, Couzens C, Staloff J, White AA, Rhodes C, Liao JM, Navathe AS.   +13 more
europepmc   +1 more source

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

Wildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie, Luyao Wang, Mengna Chen, Qinjie Chang, Hongyu Jiang, Haitao Xu, Liu Dan, Xiang Li, Yulong Wang, Xiangwei Zeng, Bin Yang, Miaowei Wang, Yonggang Jiang, Hongliang Chai, Siyuan Yang, Yajun Wang   +15 more
wiley   +1 more source

Chronic Diseases and Influenza Vaccines. [PDF]

Vaccines (Basel)
Lian R, Zhang H, An Y, Chen Z.
europepmc   +1 more source

Crisis micro‐learning: A framework for understanding the micro‐flow of policy learning and Australia's COVID‐19 response

Australian Journal of Public Administration, EarlyView.
Abstract COVID‐19 has intensified interest in crisis policy learning, yet the micro‐level interactions among political, bureaucratic, and expert actors remain underexplored. We conceptualise an ideal‐type framework for the micro‐flow of crisis learning, an ordinarily epistemic and context‐specific process of individual‐level interactions, where lessons
Neil Mortimer, Nicholas Bromfield
wiley   +1 more source

Lysosome-targeting live attenuated influenza vaccines elicit robust and broad immunity in mice. [PDF]

Nat Commun
Hao J, Wang P, Shen Q, Xi X, Tong L, Hou J, Li L, Wang Q, Liu C, Li J, Zhao H, Zhang Q, Plebani R, Chou D, Zhang L, Zhou D, Si L.   +16 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

From methods to policy: a critical appraisal of the 2024 ECDC guidance on enhanced influenza vaccines. [PDF]

Front Public Health
Ortiz de Lejarazu R, Ocaña D, Arrazola P, Orrico-Sánchez A, Redondo E, Sanz-Muñoz I, Tolosa N, Trilla A.   +7 more
europepmc   +1 more source

Fel d 1‐Expressing Plant‐Derived Bioparticle: A Novel Treatment for Cat Allergy

Allergy, EarlyView.
This study investigates the allergenicity and immunogenicity profile of a novel plant‐derived Fel d 1 bioparticle (eBP). Fel d 1 eBP promotes immune tolerance by redirecting allergic Th2 responses toward Th1 and IL‐10–producing regulatory pathways, including Bregs.
Janice A. Layhadi, Liliana Cifuentes Gutierrez, Sean T. Keane, William Fulton, Nichell A. Samson, Lily Y. D. Wu, Paulina Filipaviciute, Prista Hikmawati, Oleksandra Fedina, Ana Jimenez‐Gil, Stephen R. Durham, Guy Scadding, Guy Tropper, Louis‐Philippe Vézina, Patrick Colin, Ronald van Ree, Mohamed H. Shamji   +16 more
wiley   +1 more source

Shifting Perspective in Influenza Vaccines Efficacy: How Risk Difference Shows an Alternative View of the Comparative Efficacy Profile of Newer and Enhanced Influenza Vaccines Compared to Standard, Egg-Based Vaccines. [PDF]

Vaccines (Basel)
Colombo L, Palache A, Hadigal S.
europepmc   +1 more source