Results 1 to 10 of about 4,390 (113)

AS01B-, MF59-, and alum-based adjuvants and HIV vaccine immunogenicity: a post-hoc cross-protocol comparison of results from HVTN 100, 107, 120, and 702 [PDF]

Frontiers in Immunology
IntroductionVaccine adjuvants are crucial in HIV vaccine development, enhancing immune responses. Immune responses generated by different adjuvanted vaccines are rarely compared directly with the same vaccine antigens.MethodsThis retrospective cross ...
Ferdinando Menezes, Shiyu Chen, Nicole Grunenberg, Mookho Malahleha, Kathy Mngadi, Monde Muyoyeta, Fatima Laher, Zvavahera Mike Chirenje, Zvavahera Mike Chirenje, Linda-Gail Bekker, Paul Goepfert, Glenda E. Gray, Glenda E. Gray, Glenda E. Gray, Georgia Tomaras, Georgia Tomaras, M Juliana McElrath, M Juliana McElrath, Esper Kallas, Alison C. Roxby, Zoe Moodie   +20 more
doaj   +2 more sources

Heterologous prime-boost vaccination against H5 avian influenza: Safety and immunogenicity of a MF59-adjuvanted, cell-culture derived H5N6 vaccine [PDF]

Human Vaccines & Immunotherapeutics
With increasing H5 avian influenza cases reported globally and the potential for pandemic emergence, induction of cross-reactive antibody responses may represent an important attribute of an effective vaccine.
Esther Van Twuijver, Eve Versage, Robert L. Jacobs, Matthew Hohenboken   +3 more
doaj   +2 more sources

Specificity and functional humoral immune responses induced by the VBI-1501A eVLP HCMV gB vaccine compared to the gB/MF59 vaccine [PDF]

Human Vaccines & Immunotherapeutics
Human cytomegalovirus (HCMV) is the leading infectious cause of birth defects globally yet has no licensed vaccine. Though some HCMV glycoprotein B (gB)-based vaccine candidates, such as the MF59-adjuvanted gB vaccine (gB/MF59) elicited limited virus ...
Megan R. Connors, Krithika P. Karthigeyan, Adelaide S. Fuller, Libby Mitchell, Hannah Preston, Sergey Ananyev, Chelsea M. Crooks, Richard J. Stanton, David E. Anderson, Sallie R. Permar   +9 more
doaj   +2 more sources

A Rabies Virus Glycoprotein Subunit Vaccine Produced in Pichia pastoris Induces Neutralizing Antibodies in Mice [PDF]

Vaccines
Background: Rabies is a highly fatal zoonotic disease that causes approximately 59,000 human deaths worldwide each year. Current inactivated rabies vaccines require multiple doses and are associated with high costs.
Ye Yang, Ruo Mo, Zhuoran Hou, Han Wang, Peng Sun, Ruixi Liu, Tiantian Wang, Bin Zhang, Xuchen Hou, Yongkun Zhao, Jun Wu, Bo Liu   +11 more
doaj   +2 more sources

Combining Intramuscular and Intranasal Immunization With the MF59‐Adjuvanted Respiratory Syncytial Virus Pre‐Fusion Protein Subunit Vaccine Induces Potent Humoral and Cellular Immune Responses in Mice [PDF]

MedComm
Respiratory syncytial virus (RSV) ranks as the second leading cause of infant death globally and a significant contributor to morbidity and mortality among adults over 60 years old.
Jie Shi, Hong Lei, Yu Zhang, Chunjun Ye, Xiya Huang, Yishan Lu, Yanyan Liu, Jian Liu, Danyi Ao, Yingqiong Zhou, Jiong Li, Guangwen Lu, Xiangrong Song, Xiawei Wei   +13 more
doaj   +2 more sources

Enhanced immunogenicity of Staphylococcus aureus IsdE vaccine with SeNPs and BCG adjuvants in mice [PDF]

AMB Express
Staphylococcus aureus is a major cause of nosocomial infections and antimicrobial resistance, emphasizing the urgent need for an effective vaccine. The IsdE protein, a heme-iron transporter, has been identified as a promising antigen target.
Fatemeh Khosravani pour, Setareh Haghighat, Mohammad Hossein Yazdi, Seyed Mehdi Hassanzadeh   +3 more
doaj   +2 more sources

Adjuvanted Influenza Vaccines Versus Other Influenza Vaccines in Adults Aged ≥60 Years: A Systematic Review and Meta-Analysis of Relative Effectiveness for Preventing Influenza-Related Hospitalization [PDF]

Vaccines
Background/Objectives: Seasonal influenza vaccines have been developed to reduce the risk of severe complications in older adults, who are at increased risk of influenza-related morbidity and mortality.
Daniela Amicizia, Francesca Marchini, Irene Schenone, Elvira Massaro, Paolo Landa, Aurelien Nicosia, Andrea Orsi, Giancarlo Icardi, Filippo Ansaldi   +8 more
doaj   +2 more sources

PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): HBsAg vaccine is unable to induce Th1 immune responses. Here, immune responses and long-lived IgG responses of HBsAg-Alum, HBsAg-MF59, as well as HBsAg-MF59 were compared when formulated with PPD.
Rayhaneh Mirzaee, Fahimeh Nemati Mansoor, Mina Mirzaee, Bahareh Golkaran, Akbar Khorasani, Niloufar Rashedi, Fatemeh Asgarhalvaei, Mohammad Ali Savoji, Mehdi Mahdavi   +8 more
doaj   +1 more source

Comparative Study on the Efficacy of MF 59, ISA70 VG, and Nano-Aluminum Hydroxide Adjuvants, Alone and with Nano-Selenium on Humoral Immunity Induced by a Bivalent Newcastle+Avian Influenza Vaccine in Chickens [PDF]

Archives of Razi Institute, 2021
Newcastle disease (ND) and Avian influenza (AI) are the major problems and the most economically important viral diseases in the poultry industry; therefore, vaccination against these diseases is considered one of the most effective ways of prevention ...
M Radmehri, A Talebi, A Ameghi Roudsari, S. M Mousaviyan, M. A. J Gholipour, M Taghizadeh   +5 more
doaj   +1 more source

Evaluation of Immunogenicity of Clostridium perfringens Type B Toxoid and Inactivated FMD (O) Virus with Adjuvant (ISA70-MF59) [PDF]

Archives of Razi Institute, 2023
Foot and mouth disease (FMD) and enterotoxemia are important diseases of hoofed animals. Vaccination against livestock pathogens, especially these two diseases, plays a key role in the prevention and control of these diseases.
A Araghi, M Taghizadeh, S. R Hosseini Doust, A Paradise, S. M Azimi Dezfouli   +4 more
doaj   +1 more source