Results 191 to 200 of about 121,164 (262)

Influenza vaccines promote humoral and cellular immune responses: a randomized, double-blind, phase 3 trial. [PDF]

Nat Commun
Rodríguez-Guilarte L, Méndez C, Reyes A, Rios M, Román F, Moreno-Tapia D, Cabrera A, Rivera DB, Gutiérrez-Vera C, Palacios PA, Schilling A, Aljaro S, Bascur F, Rojas Á, Del Río C, Astudillo P, Perez CM, Perez L, Oyonarte M, Fernández Vásquez PE, Feijoo RM, Beltrán Campos D, Tovar De Sousa C, Castejón A, Grandón S, Villarroel M, Jara P, Twele L, Angélica Domínguez M, González-Aramundiz JV, Álvarez-Figueroa MJ, Yang W, Xin Q, Carreño LJ, Calvo M, Bueno SM, Peñaloza HF, González PA, Kalergis AM.   +38 more
europepmc   +1 more source

Emerging threat of avian influenza to the world's vultures

Conservation Biology, EarlyView.
Jon Morant, Andrea Santangeli, Pablo Plaza, Sergio A. Lambertucci   +3 more
wiley   +1 more source

Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors

Internal Medicine Journal, EarlyView.
Abstract Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence‐based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting.
Katherine A. Buzzard, Michael Barnett, Heidi Beadnall, Mirasol Forcadela, Lesley‐Ann Hall, Victoria G. Hall, Todd Hardy, Danny Hsu, Paul Kinsella, Mastura Monif, Sudarshini Ramanathan, Stephen W. Reddel, Sean Riminton, Douglas F. Johnson   +13 more
wiley   +1 more source

T cell immunity to seasonal Influenza A and H5N1 viruses in laboratory workers receiving annual seasonal Influenza vaccines. [PDF]

Front Immunol
Sop J, Beckey TP, Gutierrez L, Zhang L, Gebo KA, Smith KN, Blankson JN.   +6 more
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Immune Consequences of Metabolic Syndrome and Its Treatment: A Cytokine Perspective

Immunology, EarlyView.
Peripheral blood mononuclear cells (PBMCs) from individuals with metabolic syndrome (MetS) who were not using glucose‐and/or lipid lowering medication (GLLM) exhibited a broader cytokine production profile after in vitro antigen‐specific stimulation than PBMCs from individuals with MetS using such medications and from healthy donors.
Isabela Ghetti Macedo Isaac, Carolina do Prado Servian, Fernanda de Oliveira Feitosa de Castro, João Lucas Lima Calandrini de Azevedo, Ronaldo Moraes Preto, Miriam Leandro Dorta, Daniela Espíndola Antunes, Simone Gonçalves Fonseca   +7 more
wiley   +1 more source

Accomplishments and challenges in developing improved influenza vaccines: An evaluation of three years of progress toward the milestones of the influenza vaccines research and development roadmap.

Vaccine
Ostrowsky JT, Vestin NC, Mehr AJ, Ulrich AK, Bigalke L, Bresee JS, Friede MH, Gellin BG, Klugman KP, Nakakana UN, Wang TY, Weller CL, Osterholm MT, Lackritz EM, Moore KA, Influenza Vaccines R and D Roadmap Taskforce.   +15 more
europepmc   +1 more source

First Among Equals: The Case for High-quality Clinical Data in Influenza Vaccines. [PDF]

Clin Infect Dis
Manning JE, Beckers F, de Bruijn I, Sridhar S, Gurunathan S.   +4 more
europepmc   +1 more source

Immunometabolic Modulation by Low‐Dose Sodium Butyrate: PI3K/Akt/mTOR Signalling Orchestrates Macrophage Polarization to Protect Against Clostridioides difficile Colitis

Immunology, EarlyView.
Clostridioides difficile toxins TcdA and TcdB enter intestinal epithelial cells (IECs) via specific receptors, disrupt tight‐junction integrity and activate PI3K/Akt/mTOR signalling, promoting inflammasome assembly and IL‐1β release. Toxin‐induced IEC apoptosis further weakens the epithelial barrier.
Sisi Zhang, Zhou Jingxiang, Caixia Tan, Yuanyuan Xiao, Ju Zou, Biyue Tian, Anhua Wu, Chunhui Li   +7 more
wiley   +1 more source

Effectiveness of Influenza Vaccines and Duration of Protection Against Hospitalisation in England: 2022/2023 and 2023/2024 Seasons. [PDF]

Influenza Other Respir Viruses
Whitaker HJ, Kirsebom FCM, Hassell K, Quinot C, Stowe J, Hoschler K, Zambon M, Andrews NJ, Watson CH, Lopez Bernal J.   +9 more
europepmc   +1 more source