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Better influenza vaccines: an industry perspective
Journal of Biomedical Sciences, 2020 Vaccination is the most effective measure at preventing influenza virus infections. However, current seasonal influenza vaccines are only protective against closely matched circulating strains.
Juine-Ruey Chen +3 more
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Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]
, 2014 Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Temperton, Nigel J. +12 more
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Vaccines, 2018 Vaccination against influenza is the most effective approach for reducing influenza morbidity and mortality. However, influenza vaccines are unique among all licensed vaccines as they are updated and administered annually to antigenically match the ...
Surender Khurana
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Stalking influenza by vaccination with pre-fusion headless HA mini-stem. [PDF]
, 2016 Inaccuracies in prediction of circulating viral strain genotypes and the possibility of novel reassortants causing a pandemic outbreak necessitate the development of an anti-influenza vaccine with increased breadth of protection and potential for rapid ...
Carnell, George +24 more
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Pseudotype-based neutralization assays for influenza: a systematic analysis [PDF]
, 2015 The use of vaccination against the influenza virus remains the most effective method of mitigating the significant morbidity and mortality caused by this virus.
Ferrara, Francesca +11 more
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Cell culture-derived flu vaccine: Present and future
Human Vaccines & Immunotherapeutics, 2018 The benefit of influenza vaccines is difficult to estimate due to the complexity of accurately assessing the burden of influenza. To improve the efficacy of influenza vaccines, vaccine manufacturers have developed quadrivalent influenza vaccine (QIV ...
Alberto Pérez Rubio, Jose María Eiros
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Projected impact of a plant-derived vaccine on the burden of seasonal influenza in Canada
Human Vaccines & Immunotherapeutics, 2021 Objective The analysis estimates projected population outcomes resulting from the introduction of a plant-derived influenza vaccine formulated as quadrivalent virus-like particles (QVLP) in Canada.
Lauren Ramjee +7 more
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Virus-Vectored Influenza Virus Vaccines
Viruses, 2014 Despite the availability of an inactivated vaccine that has been licensed for >50 years, the influenza virus continues to cause morbidity and mortality worldwide.
Ralph A. Tripp, S. Mark Tompkins
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Challenges of Making Effective Influenza Vaccines.
Annual Review of Virology, 2020 Seasonal influenza vaccines prevent influenza-related illnesses, hospitalizations, and deaths. However, these vaccines are not as effective as other viral vaccines, and there is clearly room for improvement.
S. Gouma, E. M. Anderson, S. Hensley
semanticscholar +1 more source