Results 41 to 50 of about 207,197 (306)

Influenza nucleoprotein delivered with aluminium salts protects mice from an influenza virus that expresses an altered nucleoprotein sequence [PDF]

, 2013
Influenza virus poses a difficult challenge for protective immunity. This virus is adept at altering its surface proteins, the proteins that are the targets of neutralizing antibody.
A Endo, A Portela, AJ McMichael, Alexandria David, Andrew Pekosz, AS McKee, AT Heiny, B Zhou, CJ Wei, CS Ambrose, D Corti, D Grimm, D Zehn, DM Carragher, DT O’Hagan, E de Wit, F Crawford, F Rahman, GA Poland, GE Price, GT Belz, H Hikono, H Hohn, JB Ulmer, JE McElhaney, Jieru Wang, John W. Kappler, JP Christensen, JW Yewdell, K Thueng-in, L Guo, Laura Noges, LE Brown, LL Shu, M Schotsaert, M Wang, Megan K. L. MacLeod, MK MacLeod, MM Cox, MW LaMere, MW Lamere, N Garcon, Niyun Jin, P Marrack, Philippa Marrack, R Sebastian, RA Medina, SL Giannini, T Lambe, TM Wilkinson, U Kees, Y Furuya   +51 more
core   +7 more sources

A dose-ranging study in older adults to compare the safety and immunogenicity profiles of MF59®-adjuvanted and non-adjuvanted seasonal influenza vaccines following intradermal and intramuscular administration [PDF]

, 2014
Strategies to optimize responses to seasonal influenza vaccination in older adults include the use of adjuvants, higher antigen doses, and intradermal delivery.
Castellino, Flora, Clement, Frédéric, Del Giudice, Giuseppe, Della Cioppa, Giovanni, Galli, Grazia, Groth, Nicola, Leroux-Roels, Geert, Levin, Yotam, Lindert, Kelly, Nicolay, Uwe   +9 more
core   +1 more source

The rise of companies from emerging markets in global health governance: opportunities and challenges [PDF]

, 2014
The article analyses the involvement of pharmaceutical companies from emerging markets in global health governance. It finds that they play a central role as low-cost suppliers of medicines and vaccines and, increasingly, new technologies.
ANNE ROEMER-MAHLER, Brooks, Brown, Buse, Chaudhuri, Clarke, Cooper Ramo, Drezner, Elbe, Fleury, Gold, Knight, Levy, Meyer, Petryna, Ramamurti, Roemer-Mahler, Schoofs, Wells, Whyte, Williams, Williamson, Youde, Zimmerman   +23 more
core   +1 more source

Recombinant Influenza Vaccines [PDF]

Acta Naturae, 2012
This review covers the problems encountered in the construction and production of new recombinant influenza vaccines. New approaches to the development of influenza vaccines are investigated; they include reverse genetics methods, production of virus-like particles, and DNA- and viral vector-based vaccines.
Sedova, E., Shcherbinin, D., Migunov, A., Smirnov, Iu, Logunov, D., Shmarov, M., Tsybalova, L., Naroditskiĭ, B., Kiselev, O., Gintsburg, A.   +9 more
openaire   +3 more sources

N-glycosylation at the receptor binding site drives differences in receptor binding specificity between influenza B virus lineages

Journal of Virology
Receptor specificity plays a critical role in influenza virus host tropism and pathogenesis. Influenza A and influenza B viruses (FLUAVs and FLUBVs, respectively) utilize N-glycans with terminal sialic acids on glycoproteins decorating the surface of ...
Caroline K. Page, M. H. M. Mubassir, Pradeep Chopra, Lindsey Claire Gay, Ginger Geiger, Sean D. Ray, Justin D. Shepard, Rose J. Miller, Daniel Perez, Justin Bahl, Gerardus Josephus Boons, Stephen Mark Tompkins   +11 more
doaj   +1 more source

Impact of the coronavirus disease 2019 epidemic and a free influenza vaccine strategy on the willingness of residents to receive influenza vaccines in Shanghai, China

Human Vaccines & Immunotherapeutics, 2021
The influenza vaccine is not included in China’s national immunization program. Here, we assessed influenza vaccine coverage among Shanghai residents and estimated the impacts of the coronavirus disease 2019 (COVID-19) epidemic and a hypothetical free ...
Yehong Zhou, Jing Tang, Junjie Zhang, Qiangsong Wu   +3 more
doaj   +1 more source

Aged AG129 mice support the generation of highly virulent novel mouse-adapted DENV (1-4) viruses exhibiting neuropathogenesis and high lethality

Virus Research
Dengue virus infection in humans ranges from asymptomatic infection to severe infection, with ∼2.5 % overall disease fatality rate. Evidence of neurological manifestations is seen in the severe form of the disease, which might be due to the direct ...
Gazala Siddqui, Preeti Vishwakarma, Shikha Saxena, Varun Kumar, Sneh Bajpai, Amit Kumar, Satish Kumar, Ritika Khatri, Jaskaran Kaur, Sankar Bhattacharya, Shubbir Ahmed, Gulam Hussain Syed, Yashwant Kumar, Sweety Samal   +13 more
doaj   +1 more source

A Decade in Review: A Systematic Review of Universal Influenza Vaccines in Clinical Trials during the 2010 Decade

Viruses, 2020
On average, there are 3–5 million severe cases of influenza virus infections globally each year. Seasonal influenza vaccines provide limited protection against divergent influenza strains.
Brigette N. Corder, Brianna L. Bullard, Gregory A. Poland, Eric A. Weaver   +3 more
doaj   +1 more source

Influenza Vaccination of young children or Antibody Immune Response and Protection after Inactivated Influenza Vaccine in Children – A Literature Review [PDF]

, 2020
Influenza virus infection is a major cause of morbidity and mortality in at risk populations. Children, especially under the age of two, are at an increased risk of complications associated with influenza virus infection.
wall, danielle
core   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source