Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States
Influenza viruses continually evolve new antigenic variants, through mutations in epitopes of their major surface proteins, hemagglutinin (HA) and neuraminidase (NA). Antigenic drift potentiates the reinfection of previously infected individuals, but the
Amanda C Perofsky +25 more
doaj +1 more source
Development of an influenza virus vaccine using the baculovirus-insect cell expression system : implications for pandemic preparedness [PDF]
Key word Influenza, rHA, vaccine, baculovirus, insect cells, production, pandemic preparedness Influenza (or flu) is a highly contagious, acute viral respiratory disease that occurs seasonally in most parts of the world and is caused by influenza ...
Cox, M.M.J.
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Respiratory and systematic humoral and cellular immune response of pigs to a heterosubtypic influenza A virus infection [PDF]
The level of heterosubtypic immunity (Het-I) and the immune mechanisms stimulated by a heterosubtypic influenza virus infection were investigated in pigs. Pigs are natural hosts for influenza virus and, like humans, they host both subtypes H1N1 and H3N2.
Heinen, P.P. +3 more
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Definition of the minimal viral components required for the initiation of unprimed RNA synthesis by influenza virus RNA polymerase [PDF]
The first 11 nt at the 5' end of influenza virus genomic RNA were shown to be both necessary and sufficient for specific binding by the influenza virus polymerase.
Tiley, Laurence +5 more
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Comparative serological assays for the study of H5 and H7 avian influenza viruses. [PDF]
The nature of influenza virus to randomly mutate and evolve into new types is an important challenge in the control of influenza infection. It is necessary to monitor virus evolution for a better understanding of the pandemic risk posed by certain ...
Temperton, Nigel J. +4 more
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Research Progress on Avian Influenza Virus and Autophagy: A Review. [PDF]
Hu Z +10 more
europepmc +1 more source
A Structural View of Influenza Virus Ribonucleoprotein Complex and Its Functions. [PDF]
Liu Y, Zhang L, Lin Y, Lou Z.
europepmc +1 more source
SNHG15 Positively Regulates Influenza Virus Infection Through Its Association With miR-153 and RABL2A. [PDF]
Pushparaj S +9 more
europepmc +1 more source
Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective Antibodies. [PDF]
Adachi Y, Takahashi Y.
europepmc +1 more source

