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Reverse Vaccinology Integrated with Biophysics Techniques for Designing a Peptide-Based Subunit Vaccine for Bourbon Virus

open access: yesBioengineering
Despite the seriousness of the disease carried by ticks, little is known about the Bourbon virus. Only three US states have recorded human cases of Bourbon virus (BRBV) infection; in all cases, a tick bite was connected with the onset of the illness. The
Taghreed N. Almanaa
doaj   +1 more source

EPIDEMIOLOGICAL ANALYSIS OF AVIAN INFLUENZA IN THE AMERICAS WITH EMPHASIS ON BRAZIL: PAHO DATA FROM 2024 TO THE 25TH EPIDEMIOLOGICAL WEEK OF 2025

open access: yesBrazilian Journal of Infectious Diseases
Introduction/Objectives: Avian influenza is caused by viruses of the Orthomyxoviridae family and primarily affects birds, and in some cases can infect humans.
Roberta Maduro Prado   +2 more
doaj   +1 more source

[Endothelial protective properties of sacubitril-valsartan and drotaverine in influenza A(H1N1)pdm09 virus infection (Orthomyxoviridae: Alphainfluenzavirus: influenza A virus)].

open access: yesVoprosy virusologii
Severe influenza is characterized by damage and morphofunctional changes of the endothelium of blood vessels, which contributes to the development of hemorrhagic syndrome and can cause endothelial dysfunction. To optimize the pathogenetic therapy of influenza infection, a screening of medications with endothelial protective properties was carried out ...
V A, Marchenko   +5 more
openaire   +1 more source

Mismatched and underrepresented: bat–virus diversity and phylogeographic bias in experimental infection studies

open access: yesFrontiers in Immunology
Despite growing interest in bat–virus interactions, experimental infection studies (EIS) remain taxonomically and geographically restricted, limiting inference about bat immunology and zoonotic risk.
Luis Víquez-R   +6 more
doaj   +1 more source

Viral etiology of the acute infections of the lower respiratory tract in Cuba

open access: yesArchivo Médico de Camagüey, 2018
Background: acute respiratory infections are the main cause of mortality and morbidity worldwide, with respiratory viruses as main causative agents. Objective: to determine the paper of different respiratory viruses in the etiology of the severe acute ...
Aned Gordillo Hernández   +2 more
doaj  

FEATURES OF THE IMMUNE RESPONSE DURING INFECTION AND PROSPECTS FOR THE VACCINES CREATION [PDF]

open access: yesAnnals of Mechnikov's Institute, 2015
The influenza virus belongs to the family Orthomyxoviridae and is a major cause of respiratory infections in humans. Each year, influenza viruses cause, according to experts, 3-5 million severe course of the disease and 250 000-500 000 deaths.
Davidova T.V.
doaj  

ANP32 proteins from ticks and vertebrates are key host factors for replication of Bourbon virus across species

open access: yesJournal of Virology
Bourbon virus (BRBV) is a tick-borne virus in the genus Thogotovirus in the Orthomyxoviridae family. BRBV was initially identified as the presumptive causative agent of a fatal human infection in 2014 and has since been identified in ticks in the Midwest,
Zhenyu Zhang   +4 more
doaj   +1 more source

Features of the immune response during infection and prospects for the vaccines creation

open access: yesAnnals of Mechnikov's Institute, 2020
The influenza virus belongs to the family Orthomyxoviridae and is a major cause of respiratory infections in humans. Each year, influenza viruses cause, according to experts, 3-5 million severe course of the disease and 250 000-500 000 deaths.
T Davidova
doaj  

Emerging Respiratory Virus Threats from Influenza D and Canine Coronavirus HuPn-2018. [PDF]

open access: yesEmerg Infect Dis
Gray GC   +5 more
europepmc   +1 more source

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