PLoS Pathogens, 2020 Infections with emerging and re-emerging arboviruses are of increasing concern for global health. Tick-transmitted RNA viruses of the genus Thogotovirus in the Orthomyxoviridae family have considerable zoonotic potential, as indicated by the recent ...
Georg Kochs, Jonas Fuchs, Laura Graf
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Characterization of Viral Communities of Biting Midges and Identification of Novel Thogotovirus Species and Rhabdovirus Genus [PDF]
Viruses, 2016 More than two thirds of emerging viruses are of zoonotic origin, and among them RNA viruses represent the majority. Ceratopogonidae (genus Culicoides) are well-known vectors of several viruses responsible for epizooties (bluetongue, epizootic ...
Oleg Mediannikov +2 more
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Eight Years of Research Advances in Bourbon Virus, a Tick-borne Thogotovirus of the Orthomyxovirus Family [PDF]
Zoonoses, 2022 Bourbon virus (BRBV) was first isolated from a blood sample collected from a male patient living in Bourbon County, Kansas, during the spring of 2014. The patient later died because of complications associated with multiorgan failure.
Siyuan Hao, Jianming Qiu
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Zoonotic Infection with Oz Virus, a Novel Thogotovirus [PDF]
Emerging Infectious Diseases, 2022 Oz virus is a novel thogotovirus isolated from ticks that causes lethal infection in mice. We conducted serosurveillance of Oz virus infection among humans and wild mammals in Japan using virus-neutralization tests and ELISAs.
Haruhiko Isawa +2 more
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Involvement of a tick-borne orthomyxovirus matrix protein in vRNP nuclear export [PDF]
Journal of VirologyThogotoviruses are arthropod-borne viruses belonging to the genus Thogotovirus within the family Orthomyxoviridae. Like other orthomyxoviruses, such as the influenza A viruses (IAV), thogotoviruses replicate in the nucleus.
Vaille A. Swenson +6 more
doaj +3 more sources
Comprehensive Review of Emergence and Virology of Tickborne Bourbon Virus in the United States [PDF]
Emerging Infectious Diseases, 2023 The emergence of SARS-CoV-2 and the worldwide COVID-19 pandemic triggered considerable attention to the emergence and evolution of novel human pathogens. Bourbon virus (BRBV) was first discovered in 2014 in Bourbon County, Kansas, USA. Since its initial
Molly K. Roe +6 more
doaj +3 more sources
Experimental and evolutionary evidence for horizontal transfer of an envelope fusion protein gene between thogotoviruses and baculoviruses [PDF]
Journal of VirologyBaculoviruses are insect-specific viruses with large, double-stranded DNA genomes classified into four genera. Alphabaculoviruses, which infect lepidoptera, are further divided into group I (G1-α) and group II (G2-α). The GP64 protein, essential for cell
Bruno Milhomem Pilati Rodrigues +5 more
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ANP32 proteins from ticks and vertebrates are key host factors for replication of Bourbon virus across species [PDF]
Journal of VirologyBourbon virus (BRBV) is a tick-borne virus in the genus Thogotovirus in the Orthomyxoviridae family. BRBV was initially identified as the presumptive causative agent of a fatal human infection in 2014 and has since been identified in ticks in the Midwest,
Zhenyu Zhang +4 more
doaj +2 more sources
Development of a Double-Antigen Sandwich ELISA for Oz Virus and a Seroepidemiological Survey in Wild Boars in Miyazaki, Japan [PDF]
PathogensOz virus, an emerging tick-borne thogotovirus, has been reported to cause fatal human infection in Japan. However, its ecology and geographic distribution remain largely unknown.
Hirohisa Mekata +7 more
doaj +2 more sources
Diverse virome and potential pathogens in five tick species from metropolis surroundings of Beijing and Tianjin, China [PDF]
npj Biofilms and MicrobiomesRapid urbanization and dense populations in metropolitan areas increase the risk of tick-borne disease transmission. We profiled 139 RNA libraries of 1697 adult ticks belonging to Haemaphysalis longicornis, Haemaphysalis concinna, Dermacentor silvarum ...
Wan‑Ying Gao +13 more
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