Results 31 to 40 of about 738 (128)

Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins.

open access: yesPLoS Biology, 2019
Antagonistic interactions drive host-virus evolutionary arms races, which often manifest as recurrent amino acid changes (i.e., positive selection) at their protein-protein interaction interfaces.
Rossana Colón-Thillet   +7 more
doaj   +2 more sources

Reverse Vaccinology Integrated with Biophysics Techniques for Designing a Peptide-Based Subunit Vaccine for Bourbon Virus [PDF]

open access: yesBioengineering
Despite the seriousness of the disease carried by ticks, little is known about the Bourbon virus. Only three US states have recorded human cases of Bourbon virus (BRBV) infection; in all cases, a tick bite was connected with the onset of the illness. The
Taghreed N. Almanaa
doaj   +2 more sources

Thogotovirus

open access: yes, 2006
Haller, Otto, Kochs, Georg
core   +5 more sources

A Rare Case of Myocarditis in the Context of Norovirus Gastroenteritis. [PDF]

open access: yesCase Rep Cardiol
We present a rare case of viral myocarditis secondary to a rarely reported cause, norovirus. This case highlights the diagnostic challenges associated with acute chest pain accompanied by troponin elevation. We discuss the significance of advanced imaging techniques, particularly cardiac magnetic resonance, in the diagnosis of this condition.
Blake ES, St Clair ZT, Brummel KS.
europepmc   +2 more sources

Comparative mitogenomics elucidates the population genetic structure of Amblyomma testudinarium in Japan and a closely related Amblyomma species in Myanmar

open access: yesEvolutionary Applications, Volume 15, Issue 7, Page 1062-1078, July 2022., 2022
Abstract Ticks are the second most important vector capable of transmitting diseases affecting the health of both humans and animals. Amblyomma testudinarium Koch 1844 (Acari: Ixodidae), is a hard tick species having a wide geographic distribution in Asia. In this study, we analyzed the composition of A.
Wessam Mohamed Ahmed Mohamed   +18 more
wiley   +1 more source

Tick‐borne pathogens, including Crimean‐Congo haemorrhagic fever virus, at livestock markets and slaughterhouses in western Kenya

open access: yesTransboundary and Emerging Diseases, Volume 68, Issue 4, Page 2429-2445, July 2021., 2021
Abstract Vectors of emerging infectious diseases have expanded their distributional ranges in recent decades due to increased global travel, trade connectivity and climate change. Transboundary range shifts, arising from the continuous movement of humans and livestock across borders, are of particular disease control concern.
Tatenda Chiuya   +5 more
wiley   +1 more source

Establishment of a Replicon Reporter of the Emerging Tick-Borne Bourbon Virus and Use It for Evaluation of Antivirals

open access: yesFrontiers in Microbiology, 2020
Bourbon virus (BRBV) was first isolated from a patient hospitalized at the University of Kansas Hospital in 2014. Since then, several deaths have been reported to be caused by BRBV infection in the Midwest and Southern United States. BRBV is a tick-borne
Siyuan Hao   +7 more
doaj   +1 more source

Experimental Infection of Amblyomma americanum (Acari: Ixodidae) With Bourbon Virus (Orthomyxoviridae: Thogotovirus) [PDF]

open access: yesJournal of Medical Entomology, 2020
Abstract Following the recent discovery of Bourbon virus (BRBV) as a human pathogen, and the isolation of the virus from Amblyomma americanum (L.) collected near the location of a fatal human case, we undertook a series of experiments to assess the laboratory vector competence of this tick species for BRBV.
Marvin S, Godsey   +6 more
openaire   +2 more sources

Characterisation of putative novel tick viruses and zoonotic risk prediction. [PDF]

open access: yesEcol Evol
Tick‐borne viruses remain a substantial zoonotic risk worldwide, so knowledge of the diversity of tick viruses has potential health consequences. Through data mining and bioinformatic analyses of more than 37,800 public meta‐genomic and ‐transcriptomic data sets, we found five putative novel Alphatetra‐like viruses, four putative novel Orthomyxo‐like ...
Lin Y, Pascall DJ.
europepmc   +2 more sources

Molecular Evidence of Orthomyxovirus Presence in Colombian Neotropical Bats

open access: yesFrontiers in Microbiology, 2022
The Orthomyxoviridae family includes the genera Influenzavirus, Isavirus, Quaranjavirus, and Thogotovirus. In turn, Influenzavirus can be classified into four types: α, β, γ, and δ (Formerly A, B, C, and D), from which Alphainfluenzavirus (AIV) has the ...
Manuel Uribe   +3 more
doaj   +1 more source

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