Results 41 to 50 of about 738 (128)
Haemaphysalis longicornis (Neumann, 1901) (Acari: Ixodidae), the Asian longhorned tick, is an invasive tick species present in the USA since at least 2017 and has been detected in one-third of Virginia counties.
Alexandra N. Cumbie +2 more
doaj +1 more source
Comparative structural and functional analysis of orthomyxovirus polymerase cap-snatching domains. [PDF]
Orthomyxovirus Influenza A virus (IAV) heterotrimeric polymerase performs transcription of viral mRNAs by cap-snatching, which involves generation of capped primers by host pre-mRNA binding via the PB2 subunit cap-binding site and cleavage 10-13 ...
Delphine Guilligay +7 more
doaj +1 more source
Advances in the next generation sequencing (NGS) technologies have significantly increased our ability to detect new viral pathogens and systematically determine the spectrum of viruses prevalent in various biological samples. In addition, this approach has also helped in establishing the associations of viromes with many diseases.
Andrey A. Ayginin +10 more
wiley +1 more source
Abstract After a request from the European Commission, EFSA's Panel on Animal Health and Welfare summarised the main characteristics of 36 vector‐borne diseases (VBDs) in 36 Disease Profiles. The risk of introduction in the EU through movement of livestock or pets was assessed for each of the 36 VBDs individually, using a semiquantitative Method to ...
EFSA Panel on Animal Health and Welfare +36 more
wiley +1 more source
Heterozygous and generalist MxA super-restrictors overcome breadth-specificity trade-offs in antiviral restriction. [PDF]
Antiviral restriction factors such as MxA (myxovirus resistance protein A) inhibit many viruses. Viral escape drives restriction factors to evolve rapidly at virus-binding interfaces to regain defense.
Geiger RA +6 more
europepmc +2 more sources
Structural analysis of tumor‐related single amino acid mutations in human MxA protein
Abstract Background Human myxovirus resistant protein A (MxA), encoded by the myxovirus resistance 1 (Mx1) gene, is an interferon (IFN)‐triggered dynamin‐like multi‐domain GTPase involved in innate immune responses against viral infections. Recent studies suggest that MxA is associated with several human cancers and may be a tumor suppressor and a ...
Jia‐Li Hu +4 more
wiley +1 more source
Rapid Molecular Detection Methods for Arboviruses of Livestock of Importance to Northern Europe
Arthropod‐borne viruses (arboviruses) have been responsible for some of the most explosive epidemics of emerging infectious diseases over the past decade. Their impact on both human and livestock populations has been dramatic. The early detection either through surveillance or diagnosis of virus will be a critical feature in responding and resolving ...
Nicholas Johnson +5 more
wiley +1 more source
Soluble Host Defense Lectins in Innate Immunity to Influenza Virus
Host defenses against viral infections depend on a complex interplay of innate (nonspecific) and adaptive (specific) components. In the early stages of infection, innate mechanisms represent the main line of host defense, acting to limit the spread of virus in host tissues prior to the induction of the adaptive immune response.
Wy Ching Ng +4 more
wiley +1 more source
Bourbon Virus in Field-Collected Ticks, Missouri, USA
Bourbon virus (BRBV) was first isolated in 2014 from a resident of Bourbon County, Kansas, USA, who died of the infection. In 2015, an ill Payne County, Oklahoma, resident tested positive for antibodies to BRBV, before fully recovering.
Harry M. Savage +6 more
doaj +1 more source
Introduction. There are natural foci of Crimean-Congo hemorrhagic fever (CCHF) that vectored by Hyalomma marginatum ticks in Volga river delta (Astrakhan region, South of Russia). The circulation of Dhori virus (DHOV) (Thogotovirus: Orthomyxoviridae) has
E. V. Vakalova +7 more
doaj +1 more source

