Results 61 to 70 of about 763 (127)
Influenza A viruses are enveloped viruses belonging to the familyOrthomyxoviridaethat encompasses four more genera: Influenza B, Influenza C, Isavirus and Thogotovirus.
Renukaradhya Gourapura +3 more
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This study aimed to investigate the potentially underappreciated circulation of Bourbon virus (BRBV) and related Thogotoviruses by analyzing neutralizing antibodies in US and EU human plasma derived immunoglobulin (IG) lots.
Thomas R Kreil +2 more
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MxA variant restriction of IAV and THOV.
(A, B) MxA “nonrestrictor” variants still encoding a necessary aromatic residue at position 561 were retested in minireplicon assays to measure restriction against THOV (A) and H5N1 IAV (B) viruses.
Richard N. McLaughlin Jr (7450229) +7 more
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Oz virus is a novel thogotovirus isolated from ticks that causes lethal infection in mice. We conducted serosurveillance of Oz virus infection among humans and wild mammals in Japan using virus-neutralization tests and ELISAs.
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A modified mutagenesis strategy yields potent THOV super-restrictor variants.
(A) A modified combinatorial mutagenesis strategy with fixed F561 and four randomized L4 positions. Nonrestrictor (“NR”), restrictor (“R”), and super-restrictor (“SR”) variants are presented in order of increasing restriction activity (x-axis).
Richard N. McLaughlin Jr (7450229) +7 more
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Restriction and biochemical properties of MxA variants in THOV-infected cells.
(A) Using THOV infection of Huh7 cells expressing different MxA variants, we compared THOV restriction provided by wtMxA, MxA super-restrictors, or MxA nonrestrictors (PFFSS or ΔL4) relative to a catalytically inactive MxA (T103A) mutant.
Richard N. McLaughlin Jr (7450229) +7 more
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Exploring viral infections in honey bee colonies: insights from a metagenomic study in southern Brazil. [PDF]
da Silva LA +6 more
europepmc +1 more source
Molecular characterization of BRBV-STL.
BRBV-STL was identified in a blood sample from a hospitalized patient. The genome sequence of the virus was determined by next-generation sequencing on RNA extracted from culture supernatant of Vero cells inoculated with the patient serum.
Michael S. Diamond (106070) +11 more
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The prototype strain LEiV-K306 of the Batken virus (BKNV) was isolated from the ixodidae ticks Hyalomma marginatum Koch, 1844 collected from sheep near town Batken (Kirgizstan) in the April 1970. Later, the BKNV was isolated in Kirgizstan from the mixed pool of the Aedes caspius Pallas, 1771 and Culex hortensis Ficalbi, 1889 mosquitoes.
openaire +1 more source
Interferon-antagonistic function of the thogoto virus ML protein
Das durch Zecken übertragene Thogotovirus (THOV) gehört wie die Influenzaviren zu der Familie der Orthomyxoviren. Thogotovirus besitzt mit dem ML-Protein, einer ungespleißten, verlängerten Form des Matrix-Proteins einen Interferon (IFN)-Antagonisten ...
Büttner, Nico
core

