Results 41 to 50 of about 822,365 (179)

The dynamics of natural Plasmodium falciparum infections. [PDF]

open access: yes, 2012
BACKGROUND: Natural immunity to Plasmodium falciparum has been widely studied, but its effects on parasite dynamics are poorly understood. Acquisition and clearance rates of untreated infections are key elements of the dynamics of malaria, but estimating
Ingrid Felger (92160)   +44 more
core   +1 more source

Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

open access: yesCell Reports
Summary: Viral pandemics and epidemics pose a significant global threat. While macaque models of viral disease are routinely used, it remains unclear how conserved antiviral responses are between macaques and humans.
Kalani Ratnasiri   +17 more
doaj   +1 more source

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

open access: yesAnimal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary   +7 more
wiley   +1 more source

Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus

open access: yesMolecules, 2019
Tick-borne encephalitis virus (TBEV) is a causative agent of tick-borne encephalitis (TBE), one of the most important human infections involving the central nervous system.
Ewelina Krol   +5 more
doaj   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

open access: yesWildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie   +15 more
wiley   +1 more source

Lessons from an outbreak investigation and retrospective cohort study of influenza in a medical college in Uttar Pradesh, India, 2022

open access: yesDiscover Public Health
Background Integrated Disease Surveillance Programme, Uttar Pradesh (UP), India, notified a suspected Influenza cluster in medical college A in September 2022.
Srividya K. Vedachalam   +3 more
doaj   +1 more source

ORTHOMYXO- AND PARAMYXOVIRUSES IN MARINE MAMMALS

open access: yesЮг России: экология, развитие, 2018
. Aim. Marine mammals play the role of "sentries", standing guard over the health and functioning of marine ecosystems. The analysis of data reported in literature was carried out to understand and to evaluate a circulation of representatives of the ...
Marina G. Gulyaeva   +7 more
doaj   +1 more source

Tick-transmitted thogotovirus gains high virulence by a single MxA escape mutation in the viral nucleoprotein.

open access: yesPLoS Pathogens, 2020
Infections with emerging and re-emerging arboviruses are of increasing concern for global health. Tick-transmitted RNA viruses of the genus Thogotovirus in the Orthomyxoviridae family have considerable zoonotic potential, as indicated by the recent ...
Jonas Fuchs   +3 more
doaj   +1 more source

Ocular Manifestations of Infectious Salmon Anaemia Virus Infection in Atlantic Salmon (Salmo salar)

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT Eyes are essential sensory organs needed by teleost Atlantic salmon for high visual acuity and survival in both the wild and in aquaculture settings. In this work, we assessed the ocular manifestations of Infectious Salmon Anaemia Virus (ISAV) infection in Atlantic salmon by a cohabitation‐mediated infection assay and histological and ...
Emily Mahon   +12 more
wiley   +1 more source

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