Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. [PDF]
PLoS Pathogens, 2010 The early host response to pathogens is mediated by several distinct pattern recognition receptors. Cytoplasmic RNA helicases including RIG-I and MDA5 have been shown to respond to viral RNA by inducing interferon (IFN) production.
Leonid Gitlin +6 more
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Protective mechanism of quercetin and its derivatives in viral-induced respiratory illnesses
The Egyptian Journal of Bronchology, 2022 Globally, acute respiratory illnesses are the most commonly manifesting illness in all age group. The disease mostly affects the upper respiratory tract (URT) and is self-limiting.
Wahyu Choirur Rizky +2 more
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Биопрепараты: Профилактика, диагностика, лечение, 2021 The main triggers of new infectious diseases, including those with pandemic potential, are: spontaneous emergence of infectious strains which are more virulent for humans and contribute to transmission of pathogenic microorganisms, environmental changes,
G. G. Onishchenko +3 more
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Molecules, 2021 As a member of the Orthomyxoviridae family of viruses, influenza viruses (IVs) are known causative agents of respiratory infection in vertebrates. They remain a major global threat responsible for the most virulent diseases and global pandemics in humans.
Sphamadla E. Mtambo +7 more
doaj +1 more source
Lung Microbiome Diversity, Infection Dynamics, and Microbe-Mediated Cross-Protection. [PDF]
MicrobiologyopenThe protective role of the lung microbiome in maintaining respiratory health by promoting immune homeostasis, pathogen exclusion, and barrier integrity. Diverse microbial communities regulate immune maturation, enhance epithelial defenses, and contribute to antiviral responses, collectively preventing pathogen colonization and sustaining a balanced ...
Arooj S +7 more
europepmc +2 more sources
Recombination Resulting in Virulence Shift in Avian Influenza Outbreak, Chile
Emerging Infectious Diseases, 2004 Influenza A viruses occur worldwide in wild birds and are occasionally associated with outbreaks in commercial chickens and turkeys. However, avian influenza viruses have not been isolated from wild birds or poultry in South America. A recent outbreak in
David L. Suarez +13 more
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2023-06-14 - NCBI Viruses - Orthomyxoviridae
, 2023 Orthomyxoviridae sequences from the NCBI FTP site (https://ftp.ncbi.nlm.nih.gov/genomes/Viruses/AllNucleotide/) (downloaded 2023-06-14). Metadata from AllNuclMetadata.csv.gz (https://ftp.ncbi.nlm.nih.gov/genomes/Viruses/AllNuclMetadata/) dropping certain
Peter Kruczkiewicz (5422523)
core +1 more source
H1N1 Virus Production and Infection
Bio-Protocol, 2018 Influenza A virus is a member of orthomyxoviridae family causing wide-spread infections in human respiratory tract. Mouse infection model is widely used in antiviral research and pathogenesis study against influenza A virus. Here, we report a protocol in
Binbin Zhao +4 more
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A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]
, 2011 Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn +11 more
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Characterization of the viral microbiome in patients with severe lower respiratory tract infections, using metagenomic sequencing. [PDF]
PLoS ONE, 2012 The human respiratory tract is heavily exposed to microorganisms. Viral respiratory tract pathogens, like RSV, influenza and rhinoviruses cause major morbidity and mortality from respiratory tract disease.
Fredrik Lysholm +9 more
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