Results 11 to 20 of about 15,185 (134)

Lung Microbiome Diversity, Infection Dynamics, and Microbe-Mediated Cross-Protection. [PDF]

open access: yesMicrobiologyopen
The protective role of the lung microbiome in maintaining respiratory health by promoting immune homeostasis, pathogen exclusion, and barrier integrity. Diverse microbial communities regulate immune maturation, enhance epithelial defenses, and contribute to antiviral responses, collectively preventing pathogen colonization and sustaining a balanced ...
Arooj S   +7 more
europepmc   +2 more sources

Comparative analysis of existing platforms for the development of vaccines against dangerous and extremely dangerous viral infections with pandemic potential

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2021
The main triggers of new infectious diseases, including those with pandemic potential, are: spontaneous emergence of infectious strains which are more virulent for humans and contribute to transmission of pathogenic microorganisms, environmental changes,
G. G. Onishchenko   +3 more
doaj   +1 more source

Protective mechanism of quercetin and its derivatives in viral-induced respiratory illnesses

open access: yesThe Egyptian Journal of Bronchology, 2022
Globally, acute respiratory illnesses are the most commonly manifesting illness in all age group. The disease mostly affects the upper respiratory tract (URT) and is self-limiting.
Wahyu Choirur Rizky   +2 more
doaj   +1 more source

Influenza Viruses: Harnessing the Crucial Role of the M2 Ion-Channel and Neuraminidase toward Inhibitor Design

open access: yesMolecules, 2021
As a member of the Orthomyxoviridae family of viruses, influenza viruses (IVs) are known causative agents of respiratory infection in vertebrates. They remain a major global threat responsible for the most virulent diseases and global pandemics in humans.
Sphamadla E. Mtambo   +7 more
doaj   +1 more source

Recombination Resulting in Virulence Shift in Avian Influenza Outbreak, Chile

open access: yesEmerging Infectious Diseases, 2004
Influenza A viruses occur worldwide in wild birds and are occasionally associated with outbreaks in commercial chickens and turkeys. However, avian influenza viruses have not been isolated from wild birds or poultry in South America. A recent outbreak in
David L. Suarez   +13 more
doaj   +1 more source

H1N1 Virus Production and Infection

open access: yesBio-Protocol, 2018
Influenza A virus is a member of orthomyxoviridae family causing wide-spread infections in human respiratory tract. Mouse infection model is widely used in antiviral research and pathogenesis study against influenza A virus. Here, we report a protocol in
Binbin Zhao   +4 more
doaj   +1 more source

Characterization of the viral microbiome in patients with severe lower respiratory tract infections, using metagenomic sequencing. [PDF]

open access: yesPLoS ONE, 2012
The human respiratory tract is heavily exposed to microorganisms. Viral respiratory tract pathogens, like RSV, influenza and rhinoviruses cause major morbidity and mortality from respiratory tract disease.
Fredrik Lysholm   +9 more
doaj   +1 more source

Zoonotic Animal Influenza Virus and Potential Mixing Vessel Hosts

open access: yesViruses, 2023
Influenza viruses belong to the family Orthomyxoviridae with a negative-sense, single-stranded segmented RNA genome. They infect a wide range of animals, including humans.
Elsayed M. Abdelwhab   +1 more
doaj   +1 more source

Pandemic Scenario Tabletop Exercise

open access: yesMedEdPORTAL, 2007
State governments have been charged with planning for a worldwide or nationwide pandemic using the avian (H5N1) flu as a model since it has the potential to be the next pandemic. This is an active-learning large and small group tabletop exercise designed
Janet Lindemann   +4 more
doaj   +1 more source

Newly Designed Poxviral Promoters to Improve Immunogenicity and Efficacy of MVA-NP Candidate Vaccines against Lethal Influenza Virus Infection in Mice

open access: yesPathogens, 2023
Influenza, a respiratory disease mainly caused by influenza A and B, viruses of the Orthomyxoviridae, is still a burden on our society’s health and economic system.
Martin C. Langenmayer   +11 more
doaj   +1 more source

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