Results 141 to 150 of about 343,579 (311)

Alterations to influenza virus hemagglutinin cytoplasmic tail modulate virus infectivity [PDF]

, 1992
David Simpson, Robert A. Lamb
openalex   +1 more source

Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors

Advanced Science, EarlyView.
Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen, Riya Gupta, Yosuke M. Morizawa, Yu Qin, Xingyu Du, Cynthia Pang, Osama Al‐Dalahmah, Maura B. Dupont, Guang Yang   +8 more
wiley   +1 more source

Probing the role of membrane in neutralizing activity of antibodies against influenza virus. [PDF]

Structure
Ozgulbas DG, Tan TJC, Wen PC, Teo QW, Lv H, Ghaemi Z, Frank M, Wu NC, Tajkhorshid E.   +8 more
europepmc   +1 more source

A Phase I, Randomized, Controlled Trial to Study the Reactogenicity and Immunogenicity of a Nasal, Inactivated Trivalent Influenza Virus Vaccine in Healthy Adults [PDF]

, 2005
Scott A. Halperin, Bruce R. Smith, Kevin Clarke, John Treanor, Taoufik Mabrouk, Marc Germain   +5 more
openalex   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

The Role of Enoxaparin in Influenza Virus Infections and its Therapeutic Implications. [PDF]

J Infect Dis
Bermejo-Jambrina M, Zaderer V, Eder J, Diem G, Vlaming KE, Posch W, Geijtenbeek TBH, Wilflingseder D.   +7 more
europepmc   +1 more source

Neutralizing Epitopes of Influenza Virus Hemagglutinin: Target for the Development of a Universal Vaccine against H5N1 Lineages

, 2010
Mookkan Prabakaran, Fang He, Tao Meng, Selvaraj Madhan, Yunrui Tan, Qiang Jia, Jimmy Kwang   +6 more
openalex   +2 more sources

Improving influenza vaccine virus selection: report of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14–16 June 2010 [PDF]

, 2013
William Ampofo, Norman W. Baylor, Sarah Cobey, Nancy J. Cox, Sharon Daves, S. Edwards, Neil M. Ferguson, Gary Grohmann, Alan Hay, Jacqueline M. Katz, Kornnika Kullabutr, Linda C. Lambert, Roland Levandowski, A. C. Mishra, Arnold S. Monto, Marilda Mendonça Siqueira, Masato Tashiro, Anthony L. Waddell, Niteen Wairagkar, John Wood, Maria Zambon, Wenqing Zhang, Wenqing Zhang   +22 more
openalex   +1 more source

Influenza Virus Infection

Journal of Nippon Medical School, 2002
openaire   +3 more sources