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The influenza virus

Hospital Medicine, 1999
Influenza is a severe cause of morbidity and mortality throughout the world, resulting in annual outbreaks in all age ranges of the population. With an extensive animal reservoir the threat of emergence of a novel influenza virus, capable of causing a pandemic, has spurred research into novel therapies with which to fight the virus.
J D, Stockton, M C, Zambon
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Canine influenza virus

Veterinary Record, 2005
SIR, – In response to Mr Craig Joly’s letter ( VR , October 22, 2005, vol 157, p 527), we can confirm that action has been taken to assess the situation in the UK with respect to equine influenza in dogs.
K C, Smith   +3 more
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Influenza Virus Vectors

Biologicals, 1995
The establishment of reverse genetics methods to manipulate influenza virus genomes has allowed the generation of recombinant (transfectant) influenza viruses expressing foreign sequences. Strategies for the construction of influenza virus vectors include the insertion of foreign epitopes into influenza virus glycoproteins, the expression of ...
A, García-Sastre, P, Palese
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Avian influenza virus

Comparative Immunology, Microbiology and Infectious Diseases, 2009
Avian influenza viruses do not typically replicate efficiently in humans, indicating direct transmission of avian influenza virus to humans is unlikely. However, since 1997, several cases of human infections with different subtypes (H5N1, H7N7, and H9N2) of avian influenza viruses have been identified and raised the pandemic potential of avian ...
Chang-Won, Lee, Yehia M, Saif
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Influenza Virus Sialidase

Nature, 1960
THE sialidase of influenza virus has been investigated quantitatively using the method recently described by Warren1 for determining free sialic acid in the presence of the compound bound to muco-protein substrates. For this work, the substrate used was a mucoid derived from the nest-cementing substance of the swiftlet (Collocalia sp.).
C, HOWE, L T, LEE, H M, ROSE
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Influenza Virus Isolation

2012
The isolation of influenza viruses is important for the diagnosis of respiratory diseases in lower animals and humans, for the detection of the infecting agent in surveillance programs, and is an essential element in the development and production of vaccine.
Scott, Krauss   +2 more
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Nontoxic Influenza Virus

The Journal of Immunology, 1951
Summary The production of nontoxic influenza A virus has been described. This was accomplished by inoculating undiluted, non-mouse-adapted, allantoic fluid virus into the allantoic sac of the developing chick embryo. Mouse-adapted influenza virus would not cause nontoxic virus to be produced.
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Equine Influenza Virus

Veterinary Clinics of North America: Equine Practice, 2014
For decades the horse has been viewed as an isolated or "dead-end" host for influenza A viruses, with equine influenza virus being considered as relatively stable genetically. Although equine influenza viruses are genetically more stable than those of human lineage, they are by no means in evolutionary stasis.
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Influenza Virus Endoribonuclease

2001
The influenza virus polymerase complex contains two associated enzymatic activities, an endoribonuclease and a RNA-dependent RNA polymerase activity. Both activities have so far been observed only with the complete polymerase complex consisting of three subunits, PB1, PB2, and PA.
K, Klumpp, L, Hooker, B, Handa
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Influenza Virus Genetics

1979
Publisher Summary This chapter discusses about the structure of the influenza virion and the various gene products. It focuses on the temperature-sensitive mutants and on the structure of the RNA segments in terms of base sequence, variable and constant genes, and regions within genes, which explain the antigenic variability of the various influenza ...
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