Results 71 to 80 of about 30,685 (150)

Optimizing Research Operations and Resource Utilization in ALS Care: Insights From the Tofersen Antisense Oligonucleotide Expanded Access Protocol

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Tofersen is a gene‐targeted therapy for individuals with superoxide dismutase 1 (SOD1) (+) amyotrophic lateral sclerosis (ALS). Prior to U.S. Food and Drug Administration (FDA) approval, tofersen was made available through expanded access protocol.
Alison Wheeler, Kush Mehta, Danica Sanders, Cathy Chin, Hannah Zivalic, Judith Carey, Alexandra McCaffrey, Pravin Pant, Carl Lewenhaupt, Sarah Luppino, Gabriel Jacobs, Shea Golden, Ryan Gifford, Erica Scirocco, Mackenzie Keegan, Munaf Hatem, Taravat Yazdanian, Sanem P. Uysal, Natalie Susco, Shauna Schwartzman, Karen Branch, Kathryn E. Hall, Joanna Barnas, Jenny Lam, Jennifer Hagar, Carol Ann Hannan, Sabrina Paganoni, James D. Berry, Mark Garret, Jennifer Scalia, Suma Babu   +30 more
wiley   +1 more source

Digital Health Interventions for Informal Family Caregivers of People With First-Episode Psychosis: Systematic Review on User Experience and Effectiveness

JMIR Mental Health
BackgroundFirst-episode psychosis (FEP) imposes a substantial burden not only on the individual affected but also on their families.
Pauline Sarah Münchenberg, Dinara Yessimova, Dimitra Panteli, Tobias Kurth   +3 more
doaj   +1 more source

Urinary Incontinence and Risk of All‐Cause Mortality: A Systematic Review and Meta‐Analysis of Observational Studies

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Urinary incontinence (UI) is a prevalent condition among adults and imposes a substantial societal burden, yet its association with all‐cause mortality remains uncertain. This study systematically reviewed and quantified the association between UI and mortality risk.
Yanyan Zhou, Liwei Wang, Weijia Sun, Zhong Wang, Kuiqing Shao, Feng Xu, Zhan Gao   +6 more
wiley   +1 more source

Caregiver Burden and Associated Factors Among Informal Caregivers of Hospitalized Elderly Patients in China: A Latent Profile Analysis

Risk Management and Healthcare Policy
Hui Lv,1,2,* Shujie Yang,1,* Yuxi Zhang,1 Yingyue Wang,3 Lijiang Zhang,1 Jingjing Wang,1 Hui Jiang1 1Institutes of Health Central Plains, Xinxiang Medical University, Xinxiang, Henan Province, People’s Republic of China; 2The First Affiliated ...
Lv H, Yang S, Zhang Y, Wang Y, Zhang L, Wang J, Jiang H   +6 more
doaj  

A Buffering Role of Perceived Social Support and Resilience between Caregiver Burden and Perceived Stress among Informal Caregivers of Dementia Elderly Patients

BMC Geriatrics
Background The psychological health of caregivers of dementia patients is at risk due to excessive burden, stress, and emotional strain. The study aimed to investigate the relationship between caregiver burden, perceived stress, resilience, and perceived
Saba Zahid Hayat, Muhammad Saad, Syeda Razia Bukhari, Naila Naz   +3 more
doaj   +1 more source

The Impact of Informal Caregiving on Patient-Reported Outcomes, Psychological Well-Being and Quality of Life in Inflammatory Bowel Disease: A Systematic Review

Nursing Reports
Background/Objectives: While caregiver burden in Inflammatory Bowel Disease (IBD) is well documented, the association between informal support and patient-reported outcomes (PROs), particularly health-related quality of life (QoL) and psychological well ...
Fabrizio Benedetti, Giulia Imperatori, Valeria Amatucci, Alessio Lo Cascio, Simone Amato, Daniele Napolitano   +5 more
doaj   +1 more source

Clinician insights into pediatric temporary feeding tube management: Unseen barriers, unclear roles revealed from a prospective mixed methods study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Temporary feeding tubes are common in pediatric healthcare, but research on understanding how clinicians manage their use and understand the impact on families is limited. Existing research often overlooks clinician perspectives despite tensions between clinical priorities and family needs. This study aimed to understand clinicians'
Claire Reilly, Rebecca Packer, Jeanne Marshall, Nikhil Thapar, Jasmine Foley   +4 more
wiley   +1 more source

Caregiver burden, psychological well-being, and support needs among Swedish informal caregivers

BMC Public Health
The proportion of elderly people in the world is increasing, which increases the burden on the healthcare system and requires more formal and informal care. In Europe, informal care accounts for approximately 3.5% of GDP, and this is expected to increase.
Sonja Togmat Malki, Peter Johansson, Gerhard Andersson, Frida Andréasson, Ghassan Mourad   +4 more
doaj   +1 more source

Consensus‐Based Safety Recommendations for Informal Home Care: A Mixed Methods Study

Research in Nursing &Health, EarlyView.
ABSTRACT As home‐based care expands globally, informal caregivers are responsible for medical and nursing responsibilities, raising serious concerns about safety and risk management. This study proposes expert‐informed, safety recommendations tailored to informal caregiving in home settings.
Nida Abed, Vanessa Riberio Neves, Valerie Matarredona Perez, Daniel Monasor Ortola, Virginia Ferrer García, Bojana Knezevic, Paulo Sousa, Reinhard Strametz, Mercedes Guilabert, José Joaquín Mira   +9 more
wiley   +1 more source

Who Does Bogotá “Care” for? Care Blocks, Care Workers and the Sustainable Development Goals

Sustainable Development, EarlyView.
ABSTRACT This paper critically examines Bogotá's District Care System within the framework of urban social sustainability and the Sustainable Development Goals (SDGs). Focusing on the Care Blocks (Manzanas del Cuidado), it employs a mixed‐methods approach—legal analysis, interviews, testimonies, surveys, and InfoCuidado data—to explore the paradox of a
Valentina Montoya‐Robledo, Berta Fernández‐Gallego   +1 more
wiley   +1 more source