Results 71 to 80 of about 4,718,637 (273)

The Contribution of Temperament and Depressive Symptoms as Pathways to Informant Discrepancies on Parenting Practices [PDF]

, 2016
Despite low/moderate convergent correlations, assessment of youth typically relies on multi-informants for information across a range of domains including parenting practices.
Shishido, Yuri
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Survey on medicinal plants and spices used in Beni-Sueif, Upper Egypt

Journal of Ethnobiology and Ethnomedicine, 2011
Background This study was conducted to identify medicinal plants and spices used for medicine by the community of Beni-Sueif, Upper Egypt. Methods Ethnobotanical data from local people was collected using direct interviews and a semi-structured ...
Mohamed Abdelhalim A, AbouZid Sameh F
doaj   +1 more source

An ethnoveterinary study on medicinal plants used by the Buyi people in Southwest Guizhou, China

Journal of Ethnobiology and Ethnomedicine, 2020
Background The Buyi (Bouyei) people in Qianxinan Buyi and Miao Autonomous Prefecture, Southwest Guizhou, China, have used medicinal plants and traditional remedies for ethnoveterinary practices, such as treating domestic animals during livestock breeding,
Yong Xiong, Chunlin Long
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Global Consensus Recommendations on Improving the Safety of Chronic Total Occlusion Interventions [PDF]

Safety is of critical importance to chronic total occlusion (CTO) percutaneous coronary intervention (PCI). This global consensus statement provides guidance on how to optimise the safety of CTO) PCI, addressing the following 12 areas: 1. Set-up for safe
Wu EB, Mashayekhi K, Tsuchikane E, Vadalà G, Kalyanasundaram A, CTO Global Consensus Group. Global Consensus Recommendations on Improving the Safety of Chronic Total Occlusion Interventions., Brilakis ES   +6 more
core   +1 more source

2022 Bern Consensus Statement on shoulder injury prevention, rehabilitation, and return to sport for athletes at all participation levels

, 2022
: There is an absence of high-quality evidence to support rehabilitation and return-to-sport decisions following shoulder injuries in athletes. The Athlete Shoulder Consensus Group was convened to lead a consensus process that aimed to produce best ...
Cools, Ann, Cools, Ann M.,, H\ue4gglund, Martin, Cools, Ann M., Moller, Merete,, Blazey, P., Skazalski, Christopher,, Blazey, Paul,, Whiteley, Rod,, Gard, Suzanne,, Whiteley, Rod, Asker, M., Hägglund, M., Ardern, Clare L.,, Ardern, Clare L., Ardern, Clare, Bizzini, M., Gard, S., Horsley, Ian, Hägglund, Martin, Horsley, Ian,, Møller, M., Skazalski, C., Andersson, Stig, Asker, Martin, Møller, Merete, M\uf8ller, Merete, Ardern, C.L., Bizzini, Mario,, Haugsbø Andersson, S., Hägglund, Martin,, Cools, Ann M, Blazey, Paul, Andersson, Stig Haugsbo,, Cools, A.M., Skazalski, Christopher, Haugsbø Andersson, Stig, Schwank, A., Schwank, Ariane,, Asker, Martin,, Ardern, Clare L, Horsley, I., Gard, Suzanne, Schwank, Ariane, Andersson, Stig Haugsb\uf8, Bizzini, Mario, Whiteley, R.   +46 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source