Results 121 to 130 of about 1,137,544 (286)

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

open access: yesAdvanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen   +16 more
wiley   +1 more source

ggalign: Bridging the Grammar of Graphics and Biological Multilayered Complexity

open access: yesAdvanced Science, EarlyView.
The ggalign package provides a comprehensive framework for composable visualization built on top of ggplot2. Its primary purpose is to enable the construction of complex multi‐plot layouts with consistent observation alignment across plots, particularly for high‐dimensional data contexts such as genomics, transcriptomics, and microbiome studies ...
Yun Peng   +9 more
wiley   +1 more source

Flexible Memory Application of Nanoscale Ti–Ge–Te Thin Film as Information Storage Medium With Excellent Thermal Stability, Low Resistance Drift and Superior Bending Characteristic

open access: yesAdvanced Science, EarlyView.
Nanoscale Ti–Ge–Te films were fabricated via magnetron co‐sputtering, exhibiting the exceptional thermal stability, low resistance drift, and superior mechanical flexibility. Density functional theory reveals Ti doping can convert GeTe to a direct bandgap semiconductor and enhance covalent Ti–Te bonding. Flexible phase‐change memory devices demonstrate
Han Gu   +7 more
wiley   +1 more source

Tumor‐Tissue Boundaries as Instructive Interfaces in Breast Cancer Cell Invasion

open access: yesAdvanced Science, EarlyView.
Tumor‐tissue boundaries reprogram metastatic breast cancer cells, enhancing invasiveness through an instructive, not permissive, mechanism. Using a 3D collagen I‐based tumor‐tissue interface model, single‐cell analysis, and simulations, this study shows that all cells can transmigrate without selective filtering, highlighting a targetable process in ...
Cornelia Clemens   +6 more
wiley   +1 more source

Medical informatics

open access: bronze, 1986
J A Cooper
openalex   +1 more source

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