Results 121 to 130 of about 550,353 (340)

Biohybrid Actuators in Compact Arrangement with Embedded X Electrode

Advanced Robotics Research, EarlyView.
Selective control of multimuscle biohybrid actuators is crucial for achieving complex movements of biohybrid robots. In this study, embedded X electrodes are fabricated to selectively control multiple muscles, realizing the robotic finger's bidirectional movements.
Tingyu Li, Minghao Nie, Shoji Takeuchi
wiley   +1 more source

Challenges and Future Directions in Assessing the Quality and Completeness of Advanced Materials Safety Data for Re‐Usability: A Position Paper From the Nanosafety Community

Advanced Sustainable Systems, EarlyView.
Nanosafety data provide a guiding example for establishing best practices in data management, aligning with FAIR principles and quality criteria. This review explores existing quality assessment approaches for reliability, relevance, and completeness, emphasizing the need for harmonization and adaptation to nanomaterials and advanced materials. The aim
Verónica I. Dumit, Irini Furxhi, Penny Nymark, Antreas Afantitis, Ammar Ammar, Monica J. B. Amorim, Dalila Antunes, Svetlana Avramova, Chiara L. Battistelli, Gianpietro Basei, Cecilia Bossa, Emil Cimpan, Mihaela Roxana Cimpan, Dmitri Ciornii, Anna Costa, Camilla Delpivo, Maria Dusinska, Ana Sofia Fonseca, Steffi Friedrichs, Vasile‐Dan Hodoroaba, Danail Hristozov, Panagiotis Isigonis, Nina Jeliazkova, Nikolay Kochev, Eva Kranjc, Dieter Maier, Georgia Melagraki, Anastasios G. Papadiamantis, Tomasz Puzyn, Hubert Rauscher, Katie Reilly, Araceli Sánchez Jiménez, Janeck J. Scott‐Fordsmand, Neeraj Shandilya, Hyun Kil Shin, Gergana Tancheva, Jeaphianne P. M. van Rijn, Egon L. Willighagen, Ewelina Wyrzykowska, Martine I. Bakker, Damjana Drobne, Thomas E. Exner, Martin Himly, Iseult Lynch   +43 more
wiley   +1 more source

Research electronic data capture (REDCap) - A metadata-driven methodology and workflow process for providing translational research informatics support

Journal of Biomedical Informatics, 2009
P. Harris, Robert Taylor, R. Thielke, Jonathon Payne, N. Gonzalez, J. Conde   +5 more
semanticscholar   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Gene Ontology Consortium: The Gene Ontology (GO) database and informatics resource

Nucleic Acids Res., 2004
M. Harris, Jennifer I. Clark, A. Ireland, J. Lomax, M. Ashburner, M. Ashburner, R. Foulger, R. Foulger, K. Eilbeck, K. Eilbeck, S. Lewis, S. Lewis, B. Marshall, B. Marshall, C. Mungall, C. Mungall, J. Richter, J. Richter, G. Rubin, Gerald M. Rubin, J. Blake, C. Bult, M. Dolan, H. Drabkin, J. Eppig, Hill Dp, L. Ni, M. Ringwald, R. Balakrishnan, R. Balakrishnan, J. Cherry, J. Cherry, K. Christie, K. Christie, M. Costanzo, M. Costanzo, S. Dwight, S. Dwight, S. Engel, S. Engel, D. Fisk, D. Fisk, J. Hirschman, J. Hirschman, Eurie L. Hong, Eurie L. Hong, R. Nash, R. Nash, A. Sethuraman, A. Sethuraman, Chandra L. Theesfeld, Chandra L. Theesfeld, D. Botstein, D. Botstein, K. Dolinski, K. Dolinski, B. Feierbach, B. Feierbach, T. Berardini, T. Berardini, S. Mundodi, S. Mundodi, S. Y. Rhee, S. Y. Rhee, R. Apweiler, D. Barrell, E. Camon, E. Dimmer, Lee, R. L. Chisholm, P. Gaudet, P. Gaudet, W. Kibbe, W. Kibbe, R. Kishore, R. Kishore, E. Schwarz, E. Schwarz, P. Sternberg, P. Sternberg, M. Gwinn, L. Hannick, J. Wortman, M. Berriman, Wood, N. Delacruz, N. Delacruz, P. Tonellato, P. Tonellato, P. Jaiswal, P. Jaiswal, T. Seigfried, T. Seigfried, R. White, R. White   +94 more
semanticscholar   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

The need to separate the wheat from the chaff in medical informatics: Introducing a comprehensive checklist for the (self)-assessment of medical AI studies

Int. J. Medical Informatics, 2021
F. Cabitza, Andrea Campagner
semanticscholar   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Machine learning data sources in pediatric sleep research: assessing racial/ethnic differences in electronic health record–based clinical notes prior to model training

Frontiers in Sleep
IntroductionPediatric sleep problems can be detected across racial/ethnic subpopulations in primary care settings. However, the electronic health record (EHR) data documentation that describes patients' sleep problems may be inherently biased due to both
Mattina A. Davenport, Mattina A. Davenport, Joseph W. Sirrianni, Deena J. Chisolm, Deena J. Chisolm   +4 more
doaj   +1 more source