Results 131 to 140 of about 518,037 (342)

Machine learning data sources in pediatric sleep research: assessing racial/ethnic differences in electronic health record–based clinical notes prior to model training

open access: yesFrontiers in Sleep
IntroductionPediatric sleep problems can be detected across racial/ethnic subpopulations in primary care settings. However, the electronic health record (EHR) data documentation that describes patients' sleep problems may be inherently biased due to both
Mattina A. Davenport   +4 more
doaj   +1 more source

Memristive In‐Memory Object Detection with 128 Mb C‐Doped Ge2Sb2Te5 PCM Chip

open access: yesAdvanced Science, EarlyView.
A memristive in‐memory object detection system is presented for edge computing based on a 128 Mb phase change memory chip (40 nm, 99.99999 % yield) enabling in‐memory vector‐matrix multiplication and max computation. A novel mixed‐precision weight mapping reduces analog‐to‐digital‐converter energy by 22.3×.
Chenchen Xie   +13 more
wiley   +1 more source

Research electronic data capture (REDCap) - A metadata-driven methodology and workflow process for providing translational research informatics support

open access: yesJournal of Biomedical Informatics, 2009
P. Harris   +5 more
semanticscholar   +1 more source

Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis

open access: yesAdvanced Science, EarlyView.
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart   +4 more
wiley   +1 more source

A comprehensive classification system for lipids1

open access: yesJournal of Lipid Research, 2005
Lipids are produced, transported, and recognized by the concerted actions of numerous enzymes, binding proteins, and receptors. A comprehensive analysis of lipid molecules, “lipidomics,” in the context of genomics and proteomics is crucial to ...
Eoin Fahy   +16 more
doaj  

RUNX1/SLAMF3 Axis Drives Immunosuppression to Contribute to Colorectal Cancer Liver Metastasis by Blocking Phagocytosis and Depleting C1QC+ Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo   +10 more
wiley   +1 more source

Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation

open access: yesAdvanced Science, EarlyView.
AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang   +7 more
wiley   +1 more source

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