Results 61 to 70 of about 550,353 (340)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
A Multifunctional, Low Cost and Sustainable Neonatal Database System
ChildrenContinuous improvement in the clinical performance of neonatal intensive care units (NICU) depends on the use of locally relevant, reliable data. However, neonatal databases with these characteristics are typically unavailable in NICUs using paper-based ...
Joaquim M. B. Pinheiro +14 more
doaj +1 more source
PRINCIPLES, BASES, AND LAWS OF FUNDAMENTAL INFORMATICS
Открытое образование (Москва), 2016 This paper defines the goals and problems of fundamental informatics, formulates principal laws of information universe and constructive bases of information objects and processes.
Gennady N. Zverev
doaj +1 more source
Interactive machine learning for health informatics: when do we need the human-in-the-loop?
Brain Informatics, 2016 Machine learning (ML) is the fastest growing field in computer science, and health informatics is among the greatest challenges. The goal of ML is to develop algorithms which can learn and improve over time and can be used for predictions.
Andreas Holzinger
semanticscholar +1 more source
Encyclopedia of Database Systems, 2020 This article addresses health informatics and some of the technology advancements and issues facing health care organizations today. As the ability to communicate and share data with other institutions is rapidly advancing, so is the need for industry ...
K. Butler-Henderson
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
PI1M: A Benchmark Database for Polymer Informatics
Journal of Chemical Information and Modeling, 2020 Open source data in large scale are the cornerstones for data-driven research, but they are not readily available for polymers. In this work, we build a benchmark database, called PI1M (referring to ~1 million polymers for polymer informatics), to ...
Ruimin Ma, T. Luo
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source
, 2016 Our ability to collect “big data” has greatly surpassed our capability to analyze it, underscoring the emergence of the fourth paradigm of science, which is data-driven discovery.
Ankit Agrawal, A. Choudhary
semanticscholar +1 more source
Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams +14 more
wiley +1 more source